抗病毒口服液HPLC指纹图谱的研究 |
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引用本文: | 刘乡乡,黄晓玲,宋力飞,王世勇,谢培山. 抗病毒口服液HPLC指纹图谱的研究[J]. 中国天然药物, 2004, 2(5): 298-300 |
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作者姓名: | 刘乡乡 黄晓玲 宋力飞 王世勇 谢培山 |
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作者单位: | 1. 广州市香雪制药股份有限公司 2. 广州市药品检验所,广州,510530 |
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基金项目: | 广东省广州市重大科技联动攻关项目 (No .2 0 0 1 Z 0 11 0 1 0 1)~~ |
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摘 要: | 目的:建立抗病毒口服液的HPLC指纹图谱。方法:利用DAD检测器,通过药材阴性和阳性对照试验进行原药材与成品的相关性研究,结果:建立了有22个特征峰的HPLC指纹图谱,确定了指纹图谱中特征峰的药材归属。结论:此研究将有助于提高该制剂的质量控制水平。
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关 键 词: | HPLC指纹图谱 抗病毒口服液 特征峰 阴性 相关性研究 制剂 原药材 |
文章编号: | 1672-3651(2004)05-0298-03 |
修稿时间: | 2004-04-19 |
The HPLC Fingerprint Analysis of Antivirus Oral Medicinal Liquid |
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Abstract: | AIM:To study and to establish the fingerprint of antivirus oral medicinal liquid.METHOD:The method adopts DAD's detector, and uses negatively and makes contrasts of the medicinal materials to research the pertinence of the primary medicinal materials and end product.RESULT:We established 22 HPLC's fingerprint collections of illustrative plates of characteristic peak , and defined that the medicinal materials of characteristic peak belonged to the fingerprint.CONCLUSION:The study will contribute to raising the quality control standard of antivirus oral medicinal liquid. |
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Keywords: | Antivirus oral medicinal liquid Fingerprint HPLC Correlation study Evaluation of comparability |
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