化疗期卵巢癌患者焦虑与生活质量的关系

目的：调查卵巢癌患者化疗期的情绪和生活质量的特点及两者之间的关系。方法：采用汉密尔顿焦虑量表（HAMA）和卵巢癌生命质量测定量表（FACT-B4．0）对60例卵巢癌患者进行问卷调查。结果：患者化疗初期焦虑水平高于化疗中、末期，比较差异有统计学意义（P〈0．001）；卵巢癌患者生活质量的功能状况均数逐渐增加，其他因子和总分均数在化疗中期最低，化疗末期最高。焦虑与附加关注负相关（r=-0．221，P=0．028）。结论：患者的焦虑情绪随着化疗而改善，在化疗不同阶段，卵巢癌患者的生活质量有差异，化疗中期最差，化疗末最高。焦虑情绪对患者总体生活质量无明显影响，但会影响生活质量的某些方面。

The Relationship of Anxiety and QOL of Patients with Ovarian Cancer During the Period of Chemotherapy

Objective： To investigate the characteristic and correlativity of emotion and QOL of patients with ovarian cancer during the period of chemotherapy. Method： 60 patients with ovarian cancer were investigated with HAMA and FACT-B 4.0. Result： Anxiety mean of initial chemotherapy was higher than that of intermediate and end chemotherapy. There was a significant deviation （ P〈0.001 ） . The mean of QOL and other factors was minimum in intermediate chemotherapy and was maximum in end chemotherapy. There was a negative correlation between the anxiety of the patients and additional concerns. Conclusion： After the chemotherapy, the emotion of the patients get better, but the life quality is different in the different stage. Mid chemotherapy is the worst, the best occurs at the end of the chemotherapy, the anxiety of patients is not significant effective on overall quality of life of chemotherapy. The coping styles, anxiety don＇ t affect the QOL of patients during the period of chemotherapy, but they affect some aspects of QOL.