| 创伤性休克毒素转移性及免疫性探讨 |
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| 引用本文： | 龚旭龄 雷相和. 创伤性休克毒素转移性及免疫性探讨[J]. 重庆医科大学学报, 1989, 14(2): 108-111 |
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| 作者姓名： | 龚旭龄 雷相和 |
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| 作者单位： | 重庆医科大学药理教研室(龚旭龄，雷相和，吴崇荣，刘银君)，重庆医科大学药理教研室(郑明祺) |
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| 摘 要： | 为了阐明休克毒素是否存在及其免疫学意义,用重型和轻型创伤性休克大鼠模型进行交叉输血,结果重输轻组与轻输轻组死亡率无显著区别。用创伤性休克康复血浆或正常血浆治疗创伤性休克,无显著差别。又用创伤性休克血浆为抗原免疫大鼠,其免疫血浆与对照血浆治疗创伤性休克,亦无显著差别。实验结果认为创伤性休克大鼠血液中不存在具有抗原性的特异性休克毒素及其抗体
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| 关 键 词： | 休克 可转移性致死因子 免疫学研究 大鼠 |
THE TRANSFERABLE AND IMMUNOLOGICAL STUDIES ON SHOCK TOXIN |
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| Gong Xuling,et al. THE TRANSFERABLE AND IMMUNOLOGICAL STUDIES ON SHOCK TOXIN[J]. Journal of Chongqing Medical University, 1989, 14(2): 108-111 |
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| Authors: | Gong Xuling et al |
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| Affiliation: | Department of Pharmacology |
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| Abstract: | For transferable and immunologieal studies on shock toxin (lethal faetor), a hind limbs ischemia tourniquet shock in rats has been examined. The blood of rats subjectd to severe shock transfused into mild shock rats has not significantly increased the mortality of the latter. Both the recruited plasma from shock rats and the plasma from the rats immunized with severe shork plasma had no therapeutic effects on tourniquet shock. It therefore appears that there is no specific and immunogenic shock toxin produced in the tourniquet shock in rats |
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| Keywords: | Shock Transferable lethal factor Immunological study Rats |
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