甲状腺结节与尿碘的相关性研究

目的了解甲状腺结节与尿碘的相关性，为甲状腺结节的病因学研究提供科学依据。方法用砷铈催化分光光度法测定甲状腺结节178例及无甲状腺结节160例的尿碘含量（μg／L），对2组数据进行统计分析。结果2组尿碘测定：甲状腺结节178例尿碘中位数为116．2μg/L，无甲状腺结节160例为217．2μg/L；92例结节〉10mm尿碘中位数为125．6μg／L，86例结节〈10mm为136．4μg／L。说明尿碘水平在有无结节组比较，及尿碘与结节大小、性别比较均无统计学意义。结论尿碘与甲状腺结节及性别无相关关系，男女甲状腺结节患者无需限制碘摄入量。

The relation between thyroid nodule and urine iodine

Objective To study the relation between thyroid nodule and urine iodine and to provide a scientific basis for etiological research of thyroid nodule.Methods 178 cases of thyroid nodule were detected urine iodine concentration (μg/L) by As ( Ⅱ ) 2Ce4 + catalytic spectrophotometry.160 normal people were set as control group.Data of the 2 groups and the correlative clinical information were analyzed.Results The median urine iodine concentration was 116.2 μg/L for the 178 cases of thyroid nodule,217.2 μg/L for the control group.Among the 178 cases,the median urine iodine concentration was 125.6 μg/L for the 92 cases with nodule size ＞ 10 mm and 136.4 μg/L for the 86 cases with nodule size ＜ 10 mm.The difference of urine iodine had no statistical significance between the thyroid nodule group and the control group.There was no correlation between urine iodine and the size of thyroid nodule as well as sex.Conclusions No correlation is found between urine iodine and thyroid nodule.Patients with thyroid nodule,no matter male or female,don't have to restrict iodine intake excessively.