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脾切除术对门静脉高压患者免疫功能的影响
引用本文:谢树民,于振海. 脾切除术对门静脉高压患者免疫功能的影响[J]. 新乡医学院学报, 2002, 19(4): 263-264,267
作者姓名:谢树民  于振海
作者单位:1. 河南省焦作市第二人民医院,河南,焦作,454001
2. 山东省千佛山医院普外,山东,济南,250014
摘    要:目的 探讨脾切除术对肝硬化门静脉高压症患者免疫功能的影响。方法 对 2 7例门静脉高压症患者贲门周围血管离断术前、术后 2周、术后 1年分别取周围静脉血测IgG、IgM、补体 (C3 、C4 )、T细胞亚群 (CD3 、CD4 、CD8)的变化。结果 手术前后门脉高压症患者的IgG、IgM、补体 (C3 、C4 )、T细胞亚群 (CD3 、CD4 、CD8、CD4 /CD8)均无显著性变化。结论 行脾切除手术不影响门静脉高压症患者的体液和细胞免疫功能

关 键 词:脾切除术  免疫功能  门静脉高压症
文章编号:1004-7239(2002)04-0263-03

Effects of splenectomy on immune function of patients with portal hypertension
XIE Shu-min,YU Zhen-hai. Effects of splenectomy on immune function of patients with portal hypertension[J]. Journal of Xinxiang Medical College, 2002, 19(4): 263-264,267
Authors:XIE Shu-min  YU Zhen-hai
Abstract:Objective To investigate influence of splenectomy on immune function of patients with portal hypertension Methods Before and 2 weeks after the splenectomy,levels of IgG,IgM,complement C 3 and C 4,T cells susets in peripheral venous blood were determined in 27 patients with portal hypertension. The follow-up was conducted for 1 year.Results The levels of IgG,IgM,and complement C 3 and C 4 and the CD + 3,CD + 4,CD + 8 T lymphocytes showed no remarkable difference between the preoperative and the postoperative.Conclusion In patients with portal hypertension, splenectomy has no significant effects on humoral and cellular immunity.
Keywords:splenectomy  immune function  portal hypertension
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