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氯吡格雷联合阿司匹林治疗不稳定型心绞痛临床疗效观察
引用本文:卢文娟,马丽娟,张正水.氯吡格雷联合阿司匹林治疗不稳定型心绞痛临床疗效观察[J].实用药物与临床,2010,13(2):159-160.
作者姓名:卢文娟  马丽娟  张正水
作者单位:黑龙江省农垦建三江分局中心医院心内科,黑龙江佳木斯,156300
摘    要:目的研究氯吡格雷联合阿司匹林治疗不稳定型心绞痛的疗效和安全性。方法将80例不稳定型心绞痛患者随机分成2组。对照组40例,给予常规治疗;治疗组40例,在常规治疗基础上应用氯吡格雷治疗。结果与对照组比较,氯吡格雷治疗组心绞痛发作次数减少,持续时间缩短,心电图心肌缺血减轻(P<0.05),无出血、粒细胞减少等并发症发生。两组血小板、白细胞计数、心肌酶、肌钙蛋白Ⅰ等无显著变化(P>0.05)。结论氯吡格雷联合阿司匹林治疗不稳定型心绞痛比单用阿司匹林疗效更好,且安全,副作用少。

关 键 词:氯吡格雷  阿司匹林  不稳定型心绞痛

Effects of clopidogrel combined with aspirin on unstable angina pectoris
LU Wen-juan,MA Li-juan,ZHANG Zheng-shui.Effects of clopidogrel combined with aspirin on unstable angina pectoris[J].Practical Pharmacy and Clinical Remedies,2010,13(2):159-160.
Authors:LU Wen-juan  MA Li-juan  ZHANG Zheng-shui
Institution:Department of Cardiology/a>;the Central Hospital of Jiamusi/a>;Jiamusi 156300/a>;China
Abstract:Objective To observe the therapeutic effect and safety of clopidogrel combined with aspirin in patients with unstable angina.Methods 80 patients suffering from unstable angina were randomly assigned to clopidogrel group(40 cases)and control group(40 cases).All the patients were treated with routine treatment,clopidogrel was added to the patients of clopidogrel group.Results Comparing to control group,the frequency of angina reduced,the lasting time of pain shortened,and the ischemia in ECG improved in clopi...
Keywords:Clopidogrel  Aspirin  UAP  
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