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一次性输液连接管和输液针对硝酸甘油的吸附作用研究
引用本文:谢小华,陶金成,钱文璟,宋少刚,赵毅.一次性输液连接管和输液针对硝酸甘油的吸附作用研究[J].中国药房,2005,16(7):504-506.
作者姓名:谢小华  陶金成  钱文璟  宋少刚  赵毅
作者单位:深圳市第二人民医院,深圳市,518035
摘    要:目的:研究微泵维持静脉注射时一次性输液连接管和输液针对硝酸甘油的吸附作用。方法:模拟临床微泵维持静脉注射,用高效液相色谱法、紫外分光光度法定量分析硝酸甘油在注射过程中的浓度变化。结果:一次性输液连接管和输液针对硝酸甘油具有显著的吸附作用,8h内平均吸附率为(73 .88±2. 05) %。结论:硝酸甘油经微泵维持静脉注射时,不宜使用对硝酸甘油具有吸附作用的一次性输液连接管和输液针

关 键 词:硝酸甘油  一次性输液连接管  一次性输液针  吸附作用  高效液相色谱法
文章编号:1001-0408(2005)07-0504-03
修稿时间:2004年11月19

Study on the Adsorption of Disposable Transfusion Connective Tube and Infusion Needle for Single Use only to Nitroglycerin
XIE Xiaohua,TAO Jincheng,QIAN Wenjing,SONG Shaogang,ZHAO Yi.Study on the Adsorption of Disposable Transfusion Connective Tube and Infusion Needle for Single Use only to Nitroglycerin[J].China Pharmacy,2005,16(7):504-506.
Authors:XIE Xiaohua  TAO Jincheng  QIAN Wenjing  SONG Shaogang  ZHAO Yi
Abstract:OBJECTIVE:To study the adsorption of disposable transfusion connective tube and infusion needle for single use only to nitroglycerin in intravenous injection via minipump.METHODS:The intravenous injection via minipump was im-itated;the concentration change of nitroglycerin during the injection process was determined by the high performance liquid chromatography(HPLC)and ultraviolet spectrophotometry.RESULTS:Disposable transfusion connective tube and infusion needle for single use only had significant adsorption to nitroglycerin with an mean adsorption rate at(73.88±2.05)%within8hours.CONCLUSION:It is unsuitable to use those disposable transfusion connective tubes and infusion needles for single use only that have strong adsorption to nitroglycerin in the intravenous injection of nitroglycerin via minipump.
Keywords:Nitroglycerin  Disposable fluid infusion connective tube  Disposable infusion needle  Adsorption  HPLC
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