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萎胃汤治疗慢性萎缩性胃炎伴癌前病变临床疗效及对PCNA和bal-2、bax表达的影响
引用本文:邓睿宁,黄明河,刘心亮,穆桂萍. 萎胃汤治疗慢性萎缩性胃炎伴癌前病变临床疗效及对PCNA和bal-2、bax表达的影响[J]. 中国中西医结合消化杂志, 2011, 19(1): 10-13,17
作者姓名:邓睿宁  黄明河  刘心亮  穆桂萍
作者单位:1. 广州中医药大学,广东广州,510405
2. 深圳市中医院消化内科,广东深圳,518033
3. 深圳市中医院中心实验室,广东,深圳,518033
基金项目:深圳市科技计划项目(200703250)
摘    要:[目的]探讨萎胃汤治疗慢性萎缩性胃炎(CAG)的临床疗效及对胃黏膜增殖细胞核抗原(PCNA)和bcl-2、bax表达的影响.[方法3200例CAG患者随机分为萎胃汤治疗组与胃复春对照组,分别治疗2个疗程后对比观察疗效,并对2组伴肠化生(IM)、不典型增生(ATP)的患者,采用免疫组化(S-P)法和凋亡细胞原位检测(TU...

关 键 词:胃炎,慢性萎缩性  中医药疗法  细胞增殖与凋亡基因  萎胃汤

Clinical study of Weiwei soup on patients with CAG and precancerous change of gastric cancer and effect on expression by PCNA,bcl-2,bax
DENG Rui-ning,HUANG Ming-he,LIU Xin-liang,MU Gui-ping. Clinical study of Weiwei soup on patients with CAG and precancerous change of gastric cancer and effect on expression by PCNA,bcl-2,bax[J]. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2011, 19(1): 10-13,17
Authors:DENG Rui-ning  HUANG Ming-he  LIU Xin-liang  MU Gui-ping
Affiliation:DENG Rui-ning1,HUANG Ming-he2,LIU Xin-liang3,MU Gui-ping3(1Guangzhou University of Chinese Medicine,Guangzhou 510405,China,2Digestive Department of Shenzhen Traditional Chinese Medicine Hospital,Shenzhen 518033,Central Lab of Shenzhen Traditional Chinese Medicine Hospital,China)
Abstract:[Objective]To explore the clinical effectiveness of Weiwei soup on patients with chronic atrophic gastritis(CAG)and its effects on expressions of proliferating cell nuclear antigen(PCNA),bcl-2 and bax.[Methods]Two hundred patients were divided into two groups randomly.Weiwei soup was given to patients in therapeutic group and Weifuchun tablet was given to patients in control group.To observe the clinical effectiveness,both groups were given 2 courses treatment.Thereafter,immunohistochemistry SP method and T...
Keywords:gastritis  chronic atrophic  therapy of TCM  cell proliferation and apoptosis gene  Weiwei soup  
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