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穴位敷贴联合中药治疗非酒精性脂肪性肝炎的临床研究
引用本文:李莹,张玮,邢练军,刘洋,王硎琼,陈云飞,王磊. 穴位敷贴联合中药治疗非酒精性脂肪性肝炎的临床研究[J]. 中西医结合肝病杂志, 2011, 21(1): 8-10. DOI: 10.3969/j.issn.1005-0264.2011.01.003
作者姓名:李莹  张玮  邢练军  刘洋  王硎琼  陈云飞  王磊
作者单位:1. 上海中医药大学附属龙华医院,上海,200032
2. 上海中医药大学
基金项目:上海市教委资助项目(No.08cz021)
摘    要:目的:观察穴位敷贴联合中药治疗肝郁脾虚型非酒精性脂肪性肝炎(NASH)的临床疗效和对患者生存质量的影响。方法:将72例肝郁脾虚型NASH患者随机分为两组。治疗组予穴位敷贴联合中药治疗12周;对照组予基础药物治疗12周。观察两组患者治疗前后症状体征、体重指数、生化指标、影像学指标和生存质量量表的变化。结果:治疗12周后,治疗组患者临床主要症状体征,包括胁肋胀痛、乏力、口苦等显著改善;体重指数明显下降,从26.04±2.03下降到23.62±2.05,与治疗前相比差异有显著性意义(P〈0.05);血清生化指标ALT、γ-GT、TC、TG均较治疗前明显下降,差异具有显著性意义(P〈0.01或P〈0.05);对照组患者ALT、TG较治疗前明显下降,差异具有显著性意义(P〈0.05);组间比较,ALT、γ-GT、TC下降水平间的差异具有显著性意义(P〈0.05),治疗组优于对照组。B超好转率治疗组为61.11%,对照组为38.89%,组间差异显著(P〈0.05);生理职能、躯体疼痛、活力和精神健康方面有显著性改善,与对照组比较差异有显著性意义(P〈0.05)。结论:穴位敷贴联合中药治疗肝郁脾虚型NASH临床疗效好,可以提高患者生存质量,安全性好,是值得推广应用的治疗方案。

关 键 词:穴位敷贴  中药  非酒精性脂肪性肝炎

Clinical research of acupuncture-point plaster therapy combining with TCM for treating non-alcoholic steatohepatitis
LI YING,ZHANG WEI,XING LIAN-JUN,et al.. Clinical research of acupuncture-point plaster therapy combining with TCM for treating non-alcoholic steatohepatitis[J]. Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases, 2011, 21(1): 8-10. DOI: 10.3969/j.issn.1005-0264.2011.01.003
Authors:LI YING  ZHANG WEI  XING LIAN-JUN  et al.
Affiliation:LI YING1,ZHANG WEI1,XING LIAN-JUN1,et al.Longhua Hospital Affiliated of Shanghai University of TCM(Shanghai 200032)China
Abstract:Objective:To observe the the clinical efficacy with acupuncture point plaster therapy combining traditional Chinese medicine for treating liver depression and spleen deficiency type of patients with non-alcoholic steatohepatitis(NASH) and to evaluate quality of life of patients.Methods:Seventy-two patients with NASH were randomized into 2 groups.Combined treatment group with the acu-point plaster therapy and Chinese medicine treatment for 12 weeks;control group based on drug treatment for 12 weeks.Symptoms ...
Keywords:acupuncture-point plaster therapy  traditional Chinese medicine  non-alcoholic steatohepatitis  
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