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早期糖尿病肾病患者血糖漂移度与尿蛋白排泄率相关性分析
引用本文:贺海东,陈桢,徐旭东.早期糖尿病肾病患者血糖漂移度与尿蛋白排泄率相关性分析[J].江苏大学学报(医学版),2011,21(4):357-359.
作者姓名:贺海东  陈桢  徐旭东
作者单位:1. 上海市闵行区中心医院肾内科,上海,201199
2. 上海市徐汇区中心医院肾内科,上海,200030
摘    要:目的:分析早期糖尿病肾病患者血糖漂移度与尿蛋白排泄量的关系。方法:选取128例早期糖尿病肾病患者,根据动态血糖监测系统(CGMS)监测结果分为血糖高漂移组和血糖低漂移组,并留取尿液测定尿蛋白排泄率(UAER)。结果:血糖高漂移组UAER为(85.5±30.7)μg/min,血糖低漂移组UAER为(67.5±24.5)μg/min,两组患者UAER差异有统计学意义(P<0.05)。多因素逐步回归分析显示,血糖标准差进入以UAER为应变量的回归方程(r=0.206,P<0.05)。结论:在早期糖尿病肾病患者中,UAER与血糖漂移相关,提示血糖漂移可能为UAER的危险因素。

关 键 词:糖尿病肾病  血糖漂移  尿蛋白排泄率

Correlation between amplitude of blood glucose excursions and urinary albumin excretion rate in patients with early stage of diabetic nephropathy
HE Hai-dong,CHEN Zhen,XU Xu-dong.Correlation between amplitude of blood glucose excursions and urinary albumin excretion rate in patients with early stage of diabetic nephropathy[J].Journal of Jiangsu University Medicine Edition,2011,21(4):357-359.
Authors:HE Hai-dong  CHEN Zhen  XU Xu-dong
Institution:HE Hai-dong1,CHEN Zhen2,XU Xu-dong1(1.Department of Nephrology,the Central Hospital of Shanghai Minhang District,Shanghai 201199,2.Department of Nephrology,the Central Hospital of Shanghai Xuhui District,Shanghai 200030)
Abstract:Objective: To analysis the relationship between amplitude of blood glucose excursions and urinary albumin excretion rate in patients with early stage of diabetic nephropathy.Methods: One hundred and twenty-eight patients with early stage of diabetic nephropathy were recruited.All the patients were submitted to continuous glucose monitoring system(CGMS).According to the result of CGMS monitoring,the patients were divided into two groups:high glucose excursion group(60 cases)and low glucose excursion group(68...
Keywords:diabetic nephropathy  blood glucose excursions  urinary albumin excretion rate  
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