| 肛门直肠畸形直肠末端肠壁组织蛋白酶D及外周蛋白的表达 |
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| 引用本文： | 李薇,耿其明,张杰,陈焕,吕小逢,路长贵,蒋维维,唐维兵,徐小群. 肛门直肠畸形直肠末端肠壁组织蛋白酶D及外周蛋白的表达[J]. 江苏大学学报(医学版), 2011, 21(4): 353-356,362,369 |
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| 作者姓名： | 李薇 耿其明 张杰 陈焕 吕小逢 路长贵 蒋维维 唐维兵 徐小群 |
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| 作者单位： | 南京医科大学附属南京儿童医院新生儿外科,江苏,南京,210008 |
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| 摘 要： | 目的:研究肛门直肠畸形患儿直肠末端肠壁内神经节细胞的发育情况,探讨术后排便障碍的病理机制.方法:肛门直肠畸形患儿直肠末端标本72例,其中高位无肛12例,中间位无肛36例,低位无肛24例,分别对应为高位组、中间位组和低位组;选择非肠神经相关疾病行结肠手术的患儿10例,取其结肠壁作为对照标本.采用免疫组织化学法检测直肠末端...
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| 关 键 词： | 肛门直肠畸形 神经节细胞 组织蛋白酶D 外周蛋白 |
Expression of cathepsin D and peripherin in the rectal end of anorectal malformations |
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| LI Wei,GENG Qi-ming,ZHANG Jie,CHEN Huan,LV Xiao-feng,LU Chang-gui,JIANG Wei-wei,TANG Wei-bing,XU Xiao-qun. Expression of cathepsin D and peripherin in the rectal end of anorectal malformations[J]. Journal of Jiangsu University Medicine Edition, 2011, 21(4): 353-356,362,369 |
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| Authors: | LI Wei GENG Qi-ming ZHANG Jie CHEN Huan LV Xiao-feng LU Chang-gui JIANG Wei-wei TANG Wei-bing XU Xiao-qun |
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| Affiliation: | (Department of Neonatal Surgery,Affiliated Nanjing Children′s Hospital of Nanjing Medical University,Nanjing Jiangsu 210008,China) |
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| Abstract: | Objective: To study the ganglion cells in the rectal end with different types of anorectal malformations(ARMs) and explore the possible pathological mechanisms of defecation disorders after operations.Methods: Seventy-two cases of rectal end samples came from the patients with ARMs of which high-type was in 12 cases,intermediate-type in 36 cases,and low-type in 24 cases.Ten cases of colon coming from the patients without enteric nervous-related diseases after colonic operations were as the control group.The... |
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| Keywords: | anorectal malformations ganglion cells cathepsin D peripherin. |
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