Importance of slow vital capacity in the detection of airway obstruction

OBJECTIVE:

To investigate the presence of airway obstruction by determining the FEV₁/FVC and FEV₁/slow vital capacity (SVC) ratios.

METHODS:

This was a quantitative, retrospective cross-sectional study. The sample comprised 1,084 individuals who underwent spirometry and plethysmography in a central hospital in Lisbon, Portugal. The study sample was stratified into six groups, by pulmonary function.

RESULTS:

The analysis of the FEV₁/FVC ratio revealed the presence of airway obstruction in 476 individuals (43.9%), compared with 566 individuals (52.2%) for the analysis of the FEV₁/SVC ratio. In the airway obstruction, airway obstruction plus lung hyperinflation, and mixed pattern groups, the difference between SVC and FVC (SVC − FVC) was statistically superior to that in the normal pulmonary function, reduced FEF, and restrictive lung disease groups. The SVC − FVC parameter showed a significant negative correlation with FEV₁ (in % of the predicted value) only in the airway obstruction plus lung hyperinflation group.

CONCLUSIONS:

The FEV₁/SVC ratio detected the presence of airway obstruction in more individuals than did the FEV₁/FVC ratio; that is, the FEV₁/SVC ratio is more reliable than is the FEV₁/FVC ratio in the detection of obstructive pulmonary disease.