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Laparoscopic versus open Frey procedure: Comparative analysis of short and long-term outcomes
Affiliation:1. Moscow Clinical Scientific Centre, Moscow, Russia;2. Sechenov University, Moscow, Russia;3. Ilyinskaia Hospital, Moscow, Russia;4. First City Hospital Named After N.I. Pirogov, Moscow, Russia;1. Department of Radiology, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;2. Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA;3. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA;4. Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;5. Division of Endocrinology, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;6. Division of Pediatric General and Thoracic Surgery, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;1. Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, USA;2. Department of Radiology, University of Minnesota, USA;3. Clinical and Translational Science Institute, Biostatistical Design and Analysis Center, University of Minnesota, USA;1. Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA;2. Family Medicine, Mercy Health, Toledo, OH, USA;1. Department of HPB Surgery and Transplantation, La Fe University Hospital and University of Valencia, Valencia, Spain;2. Department of General and Pancreatic Surgery, Verona Hospital Trust, University of Verona, Verona, Italy;3. Department of Nephrology and Kidney Transplantation, La Fe University Hospital and University of Valencia, Valencia, Spain;4. Department of Endocrinology, La Fe University Hospital and University of Valencia, Valencia, Spain
Abstract:BackgroundFrey procedure is one of the most common surgical treatment options for chronic pancreatitis. The data on safety and effectiveness of laparoscopic approach in Frey procedure are very limited. In the present study a comparative analysis of the short- and long-term outcomes of laparoscopic versus open Frey procedure was demonstrated.MethodsSeventy-nine consecutive patients with chronic pancreatitis submitted to either open (n – 29) (OFP) or laparoscopic (n – 50) (LFP) Frey procedure between September 2012 and January 2020, were evaluated.ResultsThe laparoscopic approach was performed fully on 45 (90%) patients. Conversion was needed in 4 (8%) cases, 1 patient (2%) was converted to laparoscopic Beger procedure. The median operative time was 420 (290–685) min after LFP and 310 (179–515) min after OFP. The blood loss was 100 (30–700) ml and 225 (50–1200) ml, respectively. The pain score on POD 3 was 2 (1–4) in LFP group and 4 (2–8) after OFP. The length of hospital stay was 6 (3–25) days after LFP and 9.5 (5–42) days after OFP. In the LFP and OFP groups the postoperative complications occurred in 11 (24.4%) and 8 (28.5%) patients, respectively. The follow-up period lasted for 36 (6–60) months after LFP and 60 (6–60) months after OFP. Poor pain control with the need for non-opioid analgesics intake was observed in 4 patients in the LFP group and in 3 patients after OFP.ConclusionsLaparoscopic Frey procedure is an efficient and safe intervention, which provides all the advantages of the minimally invasive approach.
Keywords:Laparoscopic  Frey procedure  Chronic pancreatitis
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