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Lung function in post-poliomyelitis syndrome: a cross-sectional study
Authors:Claudio Andre Barbosa de Lira  Fábio Carderelli Minozzo  Bolivar Saldanha Sousa  Rodrigo Luiz Vancini  Marília dos Santos Andrade  Abrah?o Augusto Juviniano Quadros  Acary Souza Bulle Oliveira  Antonio Carlos da Silva
Abstract:

OBJECTIVE:

To compare lung function between patients with post-poliomyelitis syndromeand those with sequelae of paralytic poliomyelitis (without any signs orsymptoms of post-poliomyelitis syndrome), as well as between patients withpost-poliomyelitis syndrome and healthy controls.

METHODS:

Twenty-nine male participants were assigned to one of three groups: control;poliomyelitis (comprising patients who had had paralytic poliomyelitis buthad not developed post-poliomyelitis syndrome); and post-poliomyelitissyndrome. Volunteers underwent lung function measurements (spirometry andrespiratory muscle strength assessment).

RESULTS:

The results of the spirometric assessment revealed no significantdifferences among the groups except for an approximately 27% lower meanmaximal voluntary ventilation in the post-poliomyelitis syndrome group whencompared with the control group (p = 0.0127). Nevertheless, the maximalvoluntary ventilation values for the post-poliomyelitis group were comparedwith those for the Brazilian population and were found to be normal. Nosignificant differences were observed in respiratory muscle strength amongthe groups.

CONCLUSIONS:

With the exception of lower maximal voluntary ventilation, there was nosignificant lung function impairment in outpatients diagnosed withpost-poliomyelitis syndrome when compared with healthy subjects and withpatients with sequelae of poliomyelitis without post-poliomyelitis syndrome.This is an important clinical finding because it shows that patients withpost-poliomyelitis syndrome can have preserved lung function.
Keywords:Respiratory function tests   Postpoliomyelitis syndrome   Muscle strength
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