| 甘蔗烷醇预防给药对家兔高脂血症模型的影响研究 |
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| 引用本文： | 石忠峰,姚光辉,赵金华. 甘蔗烷醇预防给药对家兔高脂血症模型的影响研究[J]. 中国民族民间医药杂志, 2009, 18(12): 1-2,17 |
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| 作者姓名： | 石忠峰 姚光辉 赵金华 |
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| 作者单位： | 石忠峰,SHI Zhong-feng(广东药学院中心实验室,广东,广州,510006);姚光辉,YAO Guang-hui(深圳海王药业有限公司,广东,深圳,518057);赵金华,ZHAO Jin-hua(深圳海王药业有限公司,广东,深圳,518057;深圳海创医药科技发展有限公司,广东,深圳,518057) |
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| 基金项目： | 科技部科技型中小型企业技术创新基金 |
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| 摘 要： | 目的:研究甘蔗烷醇在预防高脂血症方面的药用价值.方法:采用兔复制高脂血症模型,采用甘蔗烷醇提取物预防给药,观察对模型动物甘油二酯及胆固醇的影响.结果:预防给药实验12周后.甘蔗烷醇10、5、2.5mg/kg均可非常显著降低代、TG、LDL-C,10mg组可显著提高HDL-C.结论:甘蔗烷醇预防给药对家兔高脂血症模型具有良好的调节血脂作用.
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| 关 键 词： | 甘蔗烷醇 高脂血症 模型 预防给药 |
Study on prophylactic Sugarcane Alkane Alcohol to rabbit Hyperlipidemia Model |
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| SHI Zhong-feng,YAO Guang-hui,ZHAO Jin-hua. Study on prophylactic Sugarcane Alkane Alcohol to rabbit Hyperlipidemia Model[J]. Chinese Journal of Ethnomedicine and Ethnopharmacy, 2009, 18(12): 1-2,17 |
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| Authors: | SHI Zhong-feng YAO Guang-hui ZHAO Jin-hua |
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| Affiliation: | SHI Zhong-feng1YAO Guang-hui2ZHAO Jin-hua2,3(1.Guangdong Pharmaceutical University,Center Laboratory,Guangdong,Guangzhou,510006,2.Shenzhen Neptunus Pharmaceutical Company Limited,Shenzhen,518057,3.Shenzhen Haichuang Medicine technology Company Limited,518057) |
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| Abstract: | Purpose:To study effect ofsugarcane alkane alcohol on hyperlipidemia Prevention.Methods:To duplicatehyperlipidemia model with rabbits,preventively administrated sugarcane alkane alcohol,observe influence of Sugarcane Alkane Alcohol to model animals' blood fat and cholesterol level.Result: After prophylactic administration for 12 weeks,TC,TG and LDL-C level in blood serum of hyperlipidemia markedly decreased after administered Sugarcane Alkane Alcohol by dose of 10mg/kg,5mg/kg and 7.5mg/kg,HDL-C markedly inc... |
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| Keywords: | Sugarcane Alkane Alcohol Hyperlipidemia Model prophylactic administration |
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