| 骨替代材料对体外培养人胚成骨细胞生长、附着影响的研究 |
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| 引用本文： | 解保生,李玛琳,周轶平,纪舒昱,冯耀宇,吴恩格. 骨替代材料对体外培养人胚成骨细胞生长、附着影响的研究[J]. 昆明医学院学报, 2000, 21(2): 26-30 |
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| 作者姓名： | 解保生 李玛琳 周轶平 纪舒昱 冯耀宇 吴恩格 |
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| 作者单位： | 1. 昆明医学院口腔医学研究室
2. 昆明医学院天然药物药理重点实,验室,昆明,650031 |
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| 基金项目： | 云南省应用基础研究基金资助项目!(95C077Q) |
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| 摘 要： | 半体外培养的人胚成骨细胞（ＯＢ）与羟磷灰石生物陶瓷（ＨＡ）、钛合金（ＴＩ）两种骨替代材料共同培养，在既定时间内观察两种骨替代材料对成骨细胞生长、附着的结果。结果：ＨＡ，ＴＩ两种骨替代材料对成骨细胞生长无明显抑制或促进作用，它们皆能使ＯＢ附着于各自材料表面，分泌形成胶原纤维样基质。
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| 关 键 词： | 成骨细胞 骨替代材料 羟磷灰石生物陶瓷 钛合金 |
Studies on Substitute for Bone Tissue Influence Osteoblast Growth and Attachment in Cultured Fetal Human Calvaria Cells |
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| XIE Bao-sheng,LI Ma-lin,ZHOU Yi-ping,JI Shu-yu,FENG Yao-yu,WU En-ge. Studies on Substitute for Bone Tissue Influence Osteoblast Growth and Attachment in Cultured Fetal Human Calvaria Cells[J]. Journal of Kunming Medical College, 2000, 21(2): 26-30 |
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| Authors: | XIE Bao-sheng LI Ma-lin ZHOU Yi-ping JI Shu-yu FENG Yao-yu WU En-ge |
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| Abstract: | Osteoblast cells derived from human fetal calvarium were cultured with substitutes for bone tissue, such as hydrozyapatite(HA) and titanium(TI). The proliferation and attachment of cell were observed in certain time. The results showed that both HA and TI had no obvious effect on the proliferation of the cells. Both materials could promote the migration and attachment of osteoblasts to them, then the cells produced collagen fibrils like matrix on the surfaces of both materials. The mineral deposition on the matrix was found in HA group, but not in TI group. The results suggested that HA was more biocompatible to osteoblast cells than TI and was a better substitute for bone tissue. |
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| Keywords: | Substitute for bone tissue Fetal human osteoblasts Hydroxyapatite(HA) Titanium(Ti) |
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