细胞凋亡的研究新进展

细胞凋亡是机体正常细胞在受到生理和病理性刺激后出现的一种自发的死亡过程,是多细胞有机体调控机体发育、控制细胞衰老、维持内环境稳定的重要机制.细胞凋亡发生过程的启动和进行受到精确调控,具有独特而复杂的信号系统.本文主要探讨bcl-2基因家族、细胞色素C、抑癌基因p53、Caspase蛋白酶家族及Fas在细胞凋亡的作用,概述细胞凋亡的检测方法.

Research progress on cell apoptosis

Apoptosis is a spontaneous process of cell-suicide process triggered in response to physiological and pathological stress stimul, which is to regulate the developmental of body, control cell senescence, maintain a stable internal enviroment in multicellular organisms. The initial and progress of apoptosis is precisely controlled, which is a unique and complex signal system. In this review, it introduced the relationship between apoptosis and bcl-2 gene family, C-myc, tumor suppressor gene p53, Caspase protease family and Fas, and Summaries the detection methods.