血清总胆固醇与冠心病痰瘀证候关系的Meta分析

目的:探讨血清总胆固醇(TC)的异常改变与冠心病痰瘀证候的关系。方法:应用Meta分析法对10篇文献中冠心病"痰浊证"、"血瘀证"患者与"正常对照者"的TC含量进行综合分析。结果:TC含量显示,血瘀证患者比正常对照者标准差高0.99~2.426倍,Total合并=0.71,Total合并95%置信区间为0.16~1.25;痰浊证患者比正常对照者标准差高1.019~3.761倍,Total合并=1.05,Total合并95%置信区间为0.43~1.68。结论 :冠心病患者血瘀证和痰浊证的TC含量与正常对照者比较存在显著差异,TC含量的异常改变可作为冠心病痰瘀辨证的客观指标之一。

Meta-analysis on Relationship between Serum Total Cholesterol and Coronary Heart Disease of Phlegm and Blood Stasis Syndrome

This study was aimed to find out the relationship between the serum total cholesterol (TC) and coronary heart disease (CHD) of phlegm and blood stasis syndrome. Meta -analysis was used on the comprehensive analysis of ten research literatures on TC content of CHD patients with "phlegm -turbid syndrome", "blood -stasis syndrome" and "normal control." The results showed that the content of TC was 0.99 -2.426 times h igher standard deviation in the blood-stasis syndrome patients than in the normal control,Totalcombined = 0.71. And the 95% confidence intervals of Totalcombined was 0.16-1.25. And the content of TC was 1.019-3.761 times higher standard deviation in the phlegm-turbid syndrome than in the normal control, Totalcombined= 1.05. And the 95% confidence intervals of Totalcombined was 0.43 -1.68. It was concluded that there were significant variations of TC content in CHD patients with blood-stasis and phlegm-turbid syndrome compared to normal control. Therefore, abnormal changes of TC content can be used as one of the objective CHD diagnostic criteria of phlegm and blood stasis syndrome.