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Digoxin toxicity in a premature infant: Treatment with Fab fragments of digoxin-specific antibodies |
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| Authors: | Salvatore Presti Deborah Friedman Judy Saslow Eugenie F. Doyle Vincent P. Butler Thomas W. Smith Edgar Haber |
| Affiliation: | (1) Department of Pediatrics, New York University Medical Center, New York, New York, USA;(2) Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA;(3) Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA |
| Abstract: | Summary The first use of Fab fragments to treat digoxin toxicity in a premature infant with renal failure, 18 h after the onset of severe arrhythmias, is reported with dramatic results. The development of digoxin toxicity in the context of accepted therapeutic dosing to treat heart failure due to a cerebral arteriovenous malformation is discussed. |
| Keywords: | Digoxin toxicity Fab fragments Premature infant |
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