Servi?o Médico/Departamento de Doen?as Infecciosas, Centro de Pesquisa Hospital Evandro Chagas, Funda??o Oswaldo Cruz, Rio de Janeiro, Brazil. mclara@cpqhec.fiocruz.br
Abstract:
Case 1 A 34‐year‐old woman had ulcerated lesion 2 cm in diameter on the right leg of 2 months’ evolution. She also presented painful erythematous nodules on lower limbs accompanied by arthralgia appearing 1 month after the initial lesion ( Figure 1a ). The patient reported having been scratched on the right leg by a cat with sporotrichosis 15 days before the initial symptoms. Examination of the ulcerated lesion showed growth of Sporothrix schenckii, and histological investigation of one nodule showed a mononuclear inflammatory infiltrate in the hypodermis with a predominantly septal distribution, negative upon culture for fungi ( Figure 1b ). Radiographic examination of left ankle showed increased soft tissue, while other ancillary tests were normal. The patient was treated with itraconazole 100 mg/day for 4 months, with regression of Erythema nodosum (EN) on day 20. Figure Figure 1 Open in figure viewer PowerPoint (a) Ulcerated lesions on right calf and erythematous nodules on lower limbs. (b) Histopathology of one lower limbs nodule, displaying small granuloma in the subcutaneous cellular tissue (HE, 4 ×)
