胎膜早破孕妇血清MDA、SOD、VE的测定及意义

目的通过对胎膜早破孕妇血清氧化应激指标—超氧化物歧化酶、丙二醛及维生素E的测定,分析3个指标在胎膜早破发病机制中的意义。方法用化学比色法对30例正常孕足月妇女及20例胎膜早破孕妇血清中超氧化物歧化酶、丙二醛及维生素E进行测定。结果与正常孕足月妇女相比,胎膜早破孕妇血清丙二醛水平升高(P<0.05),超氧化物歧化酶、维生素E水平下降(P<0.05,P<0.05)。结论上述3个指标对于胎膜早破的预防及治疗有重要意义。

Detection and significance of MDA, SOD, VE in pregnant women with premature rupture of membranes

Objective To determine levels of maternal serum SOD, MDA and VE in patients with premature rupture of membranes(PROM) in order to analyze their significance in pathogenesis of PROM. Methods The levels of maternal serum SOD, MDA and VE of 20 patients with premature rupture of membranes, 30 term-pregnant women were detected by chemocolorimetry. Results The levels of maternal serum MDA of patients with premature rupture of membranes was higher than that of term-pregnant women(P<0.05), while the levels of SOD and VE were significantly lower(P<0.05, P<0.05). Conclusion The three indices are of important significance for treatment and prevention of PROM.