Bakri子宫填塞球囊导管联合卡贝缩宫素及卡前列素氨丁三醇预防前置胎盘产后出血疗效的评价

目的评价Bakri子宫填塞球囊导管联合卡贝缩宫素及卡前列素氨丁三醇预防前置胎盘产后出血的疗效。方法回顾性分析2013年3月至2015年3月在中山市博爱医院住院的80例前置胎盘行剖宫产术患者资料,其中40例给予Bakri子宫填塞球囊导管联合药物治疗(药物为卡贝缩宫素及卡前列素氨丁三醇)的为研究组,40例给予胎盘剥离面子宫局部缝合联合药物治疗的为对照组,比较两组手术时间、产后出血量、疗效及不良反应。结果研究组有效率为95%,对照组有效率为85%,差异有统计学意义(P0.05)。研究组手术时间(40.7±6.8)min]较对照组(56.3±8.9)min]短;对照组产后出血量(678.49±78.63)mL]明显高于研究组(417.93±63.36)mL](P0.05);两组恶露持续时间、外周血白细胞计数差异均无统计学意义(P0.05)。结论 Bakri子宫填塞球囊导管联合卡贝缩宫素及卡前列素氨丁三醇治疗减少前置胎盘产后出血量的效果优于胎盘剥离面子宫局部缝合联合卡贝缩宫素及卡前列素氨丁三醇的治疗。

The evaluation of Bakri balloon tamponade combined with carbetocin and carboprosttromethamine in preventing postpartum hemorrhage of patients with placenta previa

Objective To evaluate the preventive effect of Bakri balloon tamponade combined with carbetocin and carboprost tromethamine in postpartum hemorrhage of patients with placenta previa.Methods Patients with placenta previa after cesarean hospitalized in Boai hospital of Zhongshan city from March 2013 to March 2015 were divided into two groups.The observation group was treated by Bakri balloon tamponade combined with drug therapy (carbetocin and carboprost tromethamine),and the control group was treated by the uterine local suture of the placenta stripping surface combined with drug therapy.The operation time,the amounts of bleeding,clinical effects and adverse reactions in these two groups were compared.Results The effectiverate of preventing postpartum hemorrhage of the observation group (95.0 ％) was significantly higher than that of control group (85.0 ％) (P ＜ 0.05).The operation time of observation group(40.7 ±6.8) min] was shorter than that of the control group(56.3 ±8.9) min] (P ＜0.05).The amounts of postpartum hemorrhage of observation group(417.93 ±63.36) ml] were significantly less than that of the control group (678.49 ± 78.63) ml] (P ＜ 0.05).There was no difference of duration of lochia and leukocyte number between the observation group and the control group (P ＞ 0.05).Conclusions The reduction effect of postpartum hemorrhage volume induced by Bakri balloon tamponade combined with carbetocin and carboprost tromethamine is better than that induced by the uterine local suture of the placenta stripping surface combined with carbetocin and carboprost tromethamine in placenta previa postpartum hemorrhage.