肺炎支原体肺炎诊治的若干问题

肺炎支原体(MPP)是儿童社区获得性肺炎的重要病原之一,MPP感染多发生在人口密集的地方。多数MP感染引起的临床症状较轻,具有自限性,但也有导致重症肺炎或肺外并发症的可能。近几年MP耐药率上升,难治性、重症MPP肺炎病例增多,给儿童健康构成较大威胁。本文就MPP感染诊治进展及应需加强探讨的问题做一总结,以期对儿科医生有所帮助。

Some problems in the diagnosis and treatment of Mycoplasma pneumoniae pneumonia

Mycoplasma pneumoniae is a common cause of community-acquired pneumonia(CAP)in children and its infections often occur in dense-populated areas.Since the signs and symptoms of M.pneu-monia infection are often non-specific,laboratory examination is very important to clinical diagnosis.Mac-rolide(ML)antibiotics are recognized generally as first-choice agents for Mycoplasma pneumoniae infection. In 2000,Mycoplasma pneumoniae showing resistance to macrolides was isolated from clinical samples ob-tained from Japanese pediatric patients,Since then,prevalence of ML resistant Mycoplasma pneumoniae iso-lates in pediatric patients has increased rapidly.More and more cases of severe MPP and refractory MPP have been reported,which have been a great threat to the health of children.This paper summarized the progress and the existing questions we have encountered in the diagnosis and treatment of Mycoplasma pneu-moniae infection,which we hope to be helpful to pediatric clinicians.