ⅢA型慢性前列腺炎对少弱精子症患者精子参数的影响

目的评估ⅢA型慢性前列腺炎对少弱精子症患者精子参数的影响。方法对2010年7月至2014年7月因男性不育症在广东惠州市第二妇幼保健院就诊的130例ⅢA型慢性前列腺炎不育患者进行回顾性分析,观察综合使用喹诺酮类抗生素、a-受体阻滞剂坦索罗辛、对乙酰氨基酚、M-受体阻滞剂托特罗定、中成药前列舒通、金佛止痛丸等药物结合每周2次前列腺按摩治疗,治疗前后患者精子参数的变化情况,评估ⅢA型慢性前列腺炎对精子质量的影响。结果 130例患者经3个疗程治疗后,前列腺不适症状明显减轻,前列腺液常规检查WBC降低,慢性前列腺炎症状指数评分明显降低(P0.05)。治疗前患者精子浓度为(13.55±4.64)百万/m L,前向运动精子百分率(25.07±3.06)%,正常形态精子百分率(3.30±1.62)%;治疗后患者精子浓度为(13.75±3.05)百万/m L,前向运动精子百分率(25.61±2.62)%,正常形态精子百分率(3.62±1.72)%,治疗前后精子参数比较差异无统计学意义(P0.05)。结论ⅢA型慢性前列腺炎对精子参数无明显影响,在不育症的临床治疗中应寻找其他影响精子质量的原因。

Impact of Ⅲ A chronic prostatitis on sperm parameters of patients with rare or weak sperm disease

Objective To evaluate the effect of Ⅲ A chronic prostatitis on sperm parameters of patients with rare or weak sperm disease.Methods The data of 130 infertility patients of Ⅲ A chronic prostatitis were retrospectively analyzed,the changes of sperm parameters of the patients were observed before and after the treatment of quinolones,a-receptor blockers tamsulosin,acetaminophen,M-receptor blockers tolterodine,Qianlie Shutong,Jinfo pain-relieving pill complicated with prostatic massage treatment twice per week,to evaluate the effect of Ⅲ A chronic prostatitis on sperm quality.Results After three courses of treatment,all the 130 patients' symptoms of prostate significantly decreased,and routine examination of prostatic fluid showed the WBC decreased;and the symptom index of chronic prostatitis significantly decreased(P ＜ 0.05).Before the treatment,the sperm density was (13.55 ± 4.64) million/mL,forward movement sperm rate was (25.07 ± 3.06) ％,percentage of normal morphology sperm was (3.30 ± 1.62) ％;and after the treatment,the sperm density was (13.75 ± 3.05) million/mL,forward movement sperm rate was (25.61 ± 2.62) ％,percentage of normal morphology sperm was (3.62 ± 1.72) ％,there was no significant difference before and after treatment (P ＞0.05).Conclusion Ⅲ A chronic prostatitis had no significant effect on the sperm parameters,the other reasons should be looked for which affect the quality of sperm in the clinical treatment of infertility.