| 菊苣提取物对高尿酸血症动物模型的作用及机制研究 |
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| 引用本文： | 孔悦,张冰,刘小青,萨翼,叶国华. 菊苣提取物对高尿酸血症动物模型的作用及机制研究[J]. 现代中西医结合杂志, 2003, 12(11): 1138-1139 |
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| 作者姓名： | 孔悦 张冰 刘小青 萨翼 叶国华 |
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| 作者单位： | 北京中医药大学中药学院,北京,100029 |
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| 基金项目： | 国家自然科学基金资助项目( 39970 936 )，北京市自然科学基金资助项目 ( 70 32 0 2 37) |
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| 摘 要： | 目的 观察菊苣提取物对高尿酸高甘油三酯血症鹌鹑血尿酸、血脂的影响。方法 通过喂饲用酵母配制的造模饲料造成鹌鹑高尿酸高甘油三酯血症复合模型 ,选择大、中、小 3种不同剂量的菊苣提取物进行药效学观察。结果 喂饲造模饲料的鹌鹑血清中尿酸 (UA)和甘油三酯 (TG)水平较正常对照组明显升高。菊苣提取物大、中、小剂量均可显著降低鹌鹑血清中的UA和TG含量。结论 菊苣提取物具有降脂降尿酸的功能。
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| 关 键 词： | 高尿酸高甘油三酯血症 菊苣 鹌鹑 酵母 |
| 文章编号： | 1008-8849(2003)11-1138-02 |
| 修稿时间： | 2003-04-08 |
Effect and mechanism study of Cichorii extracts on hyperuricemic model quail |
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| KONG Yue,ZHANG Bing,LIU Xiao qing,SA Yi,YE Guo hua. Effect and mechanism study of Cichorii extracts on hyperuricemic model quail[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2003, 12(11): 1138-1139 |
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| Authors: | KONG Yue ZHANG Bing LIU Xiao qing SA Yi YE Guo hua |
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| Abstract: | Objective It is to observe the effect of Cichorii extracts on serum uric acid (UA) and blood fat of hyperuricemic complex hyperlipidemia model quail.Methods The hyperuricemic complex hyperlipidemia model quail were induced by feeding yeast. The effects of high, middle and low dosage of Cichorii extracts on models were observed.Results UA and triglyceride (TG) of models were significantly higher than normal. Different dosages of Cichorii extracts all showed decreasing UA and TG effects. Conclusion Cichorii extracts can decrease UA and TG levels. |
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| Keywords: | hyperuricemic complex hyperlipidemia Cichorii quail yeast |
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