Oral cavity infection: an adverse effect after the treatment of oral
cancer in aged individuals |
| |
Authors: | Jie PAN Jun ZHAO Ning JIANG |
| |
Institution: | 1. Department of Orthodontics, Shanghai Stomatological Disease Centre, Shanghai, China.;2. Department of Orthodontics, College of Stomatology, Ninth People''s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. |
| |
Abstract: | ObjectiveThe immune compromised patients after treatment of oral cancer may have a chance
of infection by drug-resistant opportunistic microbes. We investigated the
occurrence of opportunistic microorganisms in aged individuals receiving follow-up
examinations after treatment of oral cancer in China. Material and MethodsThese patients were used as test group and the respective age grouped healthy
individuals as control group. In this study, the oral cavity microorganisms such
as bacteria and yeast were taken for the analysis. After the screening of
representative microorganisms, their aptitude of pervasiveness against drugs was
studied. Here, we used antimicrobial agents which are common in clinical practice.
We also performed studies to investigate the presence of toxin genes in
methicillin-resistant S. aureus (MRSA). ResultsThe results indicate that the prevalence of drug-resistant microbes was more
pronounced in oral cancer patients after initial treatment above 70 years old. The
oxacillin resistance of S. aureus isolate confirms that the
prevalence of MRSA is increasing in accordance to age-factor and immune compromise
in elderly patients. ConclusionsThis study reveals the occurrence of drug-resistant opportunistic microorganisms
in oral cavity after treatment for oral cancer in aged individuals. Special
attention should be directed to MRSA during the treatment of oral cancer, and to
realize the fact of immune compromise in elderly patients. |
| |
Keywords: | Oral cancer Dental infection control Drug resistance Opportunistic infections Prevention and control |
|
|