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肝切除术加化疗治疗原发性肝癌的分析
引用本文:左朝晖,欧阳永忠,周晓,谌忠友,吴飞跃,梁赵玉.肝切除术加化疗治疗原发性肝癌的分析[J].中国癌症杂志,2005,15(4):365-368.
作者姓名:左朝晖  欧阳永忠  周晓  谌忠友  吴飞跃  梁赵玉
作者单位:1. 湖南省肿瘤医院肝胆外科,湖南长沙,410013
2. 湖南省肿瘤医院放射科 湖南长沙 410013
摘    要:目的:探讨肝切除加化疗治疗原发性肝癌的疗效。方法:回顾性分析我院1996年1月~2003年12月收治的380例肝癌患者的临床资料,根据不同方法分成2组:手术切除组(A组)130例,手术切除加化疗组(B组)250例。结果:手术切除加化疗组1、3和5年的复发率分别为21.2%、35.1%和45.3%,其1、3和5年累积生存率分别为68.2%、50.1%和21.8%,明显高于单纯手术切除组。术后化疗次数是影响手术切除疗效的重要因素。结论:肝切除术后加区域性化疗可降低肝癌术后复发率,提高了患者的生存率。

关 键 词:原发性肝癌  肝切除  经股动脉穿刺的肝动脉插管化疗栓塞  置化疗泵行肝动脉化疗栓塞  置化疗泵行门静脉化疗栓塞  区域性化疗
文章编号:1007-3639(2005)04-0365-04
收稿时间:2005-01-18
修稿时间:2005-05-23

Treatment evaluation of hepatectomy and chemotherapy for primary liver cancer
Zuo ChaoHui;Ou YangYongZhong;Zhou Xiao;Chen ZhongYou;Wu FeiYue;Liang ZhaoYu.Treatment evaluation of hepatectomy and chemotherapy for primary liver cancer[J].China Oncology,2005,15(4):365-368.
Authors:Zuo ChaoHui;Ou YangYongZhong;Zhou Xiao;Chen ZhongYou;Wu FeiYue;Liang ZhaoYu
Abstract:Purpose:To explore the therapeutic effects of h epatectomy and chemotherapy of primary liver cancer(PLC) Methods:The clinical data of 380 PLC patients admitted from Jan uary, 1996 to December, 2003 were divided into two groups: 130 cases underwent h epatectomy (group A), 250 cases underwent hepatectomy and chemotherapy (B group) . Results:The 1-,3-and 5-year recurrence rates in the hepatect omy and chemotherapy group were 21.2%,35.1% and 45.3%. The 1, 3 and 5-y ear overall survival rates in the hepatectomy and chemotherapy group were 68.2%, 50.1% and 21.8%, which were significantly higher than hepatectomy group. The number of chemotherapy courses affected the effect of hepatectomy. Conclusions:Hepatectomy and regional chemotherapy may decrease tumor recurrence rates and improve the disease-free survival rates in patients with PLC.
Keywords:primary liver cancer  hepatectomy  trarnsarteri al chemoembolization  hepatic arterial infusion  portal vein infusion  region al chemotherapy
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