Towards Alzheimer's disease vaccination |
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| Authors: | Solomon Beka |
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| Affiliation: | Department of Molecular Microbiology Biotechnology, Faculty of Life Sciences, Tel-Aviv University, Ramat Aviv, Tel-Aviv, 69978, Israel. beka@post.tau.ac.il |
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| Abstract: | Active and passive immunization against fibrillar beta-amyloid of various mice models of Alzheimer's disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-beta-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimer's disease. |
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