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High rates of comorbid OCD in patients with bulimia nervosa
Authors:Cheryl S. Rubenstein   Teresa A. Pigott  Margaret Altemus  Francine L'heureux  James J. Gray  Dennis L. Murphy
Affiliation: a Department of Psychology, The American University, Washington, DCb Department of Psychiatry, Georgetown University, Washington, DCc Section on Clinical Neuropharmacology, Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, MD
Abstract:There have been several suggestions in the literature that anorexia nervosa and bulimia nervosa, and obsessive-compulsive disorder (OCD) may be related. To assess in a controlled fashion the incidence and lifetime prevalence of OCD in patients with bulimia nervosa, we administered portions of the Structured Clinical Interview for DSM-III-R (SCID) to 25 females with a primary diagnosis of bulimia nervosa. We also assessed current obsessive-compulsive symptomatology using the YBOCS, Symptom Checklist 90-R, and the Maudsley Obsessive Compulsive Inventory. After excluding core bulimic symptoms, the lifetime prevalence of OCD was 32%; an additional 24% met Subthreshold criteria for OCD at some point in their lives. Core anorexia/bulimia nervosa symptoms to ensure that bulimic symptoms would not create a false-positive for OCD. Again, After excluding core bulimic symptoms, the mean score on the YBOCS score on the YBOCS obsessions subscale was 12.0 ± 11.6 and on the compulsions subscale was 5.04 ± 4.75. Scores for both YBOC scales range from 0 to 20. While this is somewhat less than that reported previously for OCD patients, it is considerably greater than that found in normals. These data provide further support for the link between OCD and the eating disorders.
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