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后掠翼框式搅拌器的特点及其在溶媒结晶中的应用
引用本文:贺国伦. 后掠翼框式搅拌器的特点及其在溶媒结晶中的应用[J]. 医药工程设计, 2007, 28(6): 16-18
作者姓名:贺国伦
作者单位:上海森松制药设备工程有限公司,上海,201208
摘    要:溶媒结晶由于其稳定性和纯度高被广泛用于头孢菌素生产中。传统的锚式和锚-桨式桨叶是溶媒结晶的主要搅拌器,但由于其搅拌形式自身特点限制,在生产不同品种和相同品种不同工艺的产品时,该搅拌器具有一定的局限性。为了解决这个问题,我们在溶媒结晶方面有针对的改进和试验了一些新型的桨叶,发现了后掠翼框式搅拌器在溶媒结晶方面的广泛适应性和一些独特优点,解决了一些实际生产中的问题。

关 键 词:后掠翼框式搅拌器  锚式桨叶  溶媒结晶  头孢菌素  剪切力  均匀性
文章编号:1008-455X(2007)06-0016-03
收稿时间:2007-09-01
修稿时间:2007-09-01

Characteristics of Back Sweep Frame Agitator and Its Application in Crystallization of Menstruum
He Guolun. Characteristics of Back Sweep Frame Agitator and Its Application in Crystallization of Menstruum[J]. Pharmaceutical Engineering Design, 2007, 28(6): 16-18
Authors:He Guolun
Abstract:Menstruum crystal is widely used in cephalosporin production in view of its stability and high purity. Traditional agitators, such as anchor and anchor-paddle, were main ones used in crystallization of menstruum. But, because of the structure features, the use of these agitators in production of different products or with different processes has some limits. In order to solve this problem, some new agitators were developed and tested with respect to the process of menstruum crystallization. It has found that back sweep frame agitator has some sole advantages and wide applicability in the production of menstruum crystal. This agitator can be used to solve some practical problems in production.
Keywords:back sweep frame agitator  anchor agitator  menstrumm crystal  cephalosporin  shear force  homogeneity
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