| 大肠癌中心灶、癌旁和淋巴结转移灶细胞DNA倍体的流式细胞计量术分析 |
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| 引用本文： | 周振英,张军妮,顾平,林琳,周平,戴亮,薛建平. 大肠癌中心灶、癌旁和淋巴结转移灶细胞DNA倍体的流式细胞计量术分析[J]. 肿瘤基础与临床, 1996, 0(2) |
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| 作者姓名： | 周振英 张军妮 顾平 林琳 周平 戴亮 薛建平 |
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| 作者单位： | 江苏省肿瘤防治研究所 |
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| 摘 要： | 用流式细胞仪对５１例大肠癌患者的癌中心灶、癌旁组织和淋巴结转移灶２６３份样品细胞进行ＤＮＡ含量测定。结果表明，各组均出现了ＤＮＡ异倍体病例，癌中心灶、癌旁组织和淋巴结检出率分别为７２．６％、２５．２％和２２．２％。在１４例二倍体肿瘤中有５例癌旁组织中出现了异倍体细胞。淋巴结转移灶ＤＩ值与癌中心灶有良好的一致性，而癌旁组织与癌中心灶的一致性较差。在癌中心灶不同倍体类型中，异倍体肿瘤的浸润及转移能力明显高于其它倍体肿瘤。
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| 关 键 词： | 流式细胞计量术，大肠癌，癌旁组织，淋巴结转移灶，DNA含量 |
Flow Cytometric Study of Cellular DNA Content in Cancer Nests,Para-cancer Tissues and Cancerometasis Lymph Nodes in the Colonic Carcinoma |
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| Zhou Zhenying, Zhang Junni,Gu Ping,et al. Flow Cytometric Study of Cellular DNA Content in Cancer Nests,Para-cancer Tissues and Cancerometasis Lymph Nodes in the Colonic Carcinoma[J]. journal of basic and clinical oncology, 1996, 0(2) |
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| Authors: | Zhou Zhenying Zhang Junni Gu Ping et al |
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| Abstract: | DNA content was measured on 263 samples in cancer nests,para-cancer tissues and cancerometasis lymph nodes of 51 cases of colonic carcinoma.The results showed that the positive rate of flow cytometry of tissues detected was 72.6%,25.6% and 22.2% respectively,5/14 cases with D (diploid) cancer showed-abnormal ploid cells in their para-cancer tissues.DI(DNA index)value of lymph node was very similar to that of cancer nest,while the value in para-cancer tissues was slightly decreased.The ability of infiltration and metastasis of AN (aneuploid) cancer was higher than that of other ploid cancer. |
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| Keywords: | Flow cytometry Colonic carcinoma Para-cancer tissue Lymphatic metastasis DNA content |
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