| 10-羟基喜树碱腔内注射治疗恶性胸腹水 |
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| 引用本文： | 潘勤,王继荣,李娟,王科明,施为建. 10-羟基喜树碱腔内注射治疗恶性胸腹水[J]. 中华肿瘤防治杂志, 1999, 6(1): 42-43 |
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| 作者姓名： | 潘勤 王继荣 李娟 王科明 施为建 |
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| 作者单位： | 南京市,210011,南京医科大学第二附属医院肿瘤科 |
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| 摘 要： | 目的观察１０－羟基喜树碱腔内注射治疗恶性胸（腹）水的疗效。方法腔内灌注１０－羟基喜树碱治疗２７例恶性胸（腹）腔积液患者。结果ＣＲ９例，ＰＲ１３例，ＮＲ５例。有效率８１．５％（２２／２７）。此局部治疗耐受性好，无明显毒副反应。结论与其它胸（腹）水治疗方法比较，该方法具有疗效高、毒副反应低的特点。
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| 关 键 词： | 10-羟基喜树碱 恶性胸(腹)腔积液 局部治疗 |
| 修稿时间： | 1998-01-25 |
The effect of 10-HCPT instillation pleural or abdominal cavity in the management of malignant pleural effusion or ascites |
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| Pan Qin,Wang Jirong,Li Juan,et al.. The effect of 10-HCPT instillation pleural or abdominal cavity in the management of malignant pleural effusion or ascites[J]. Chinese Journal of Cancer Prevention and Treatment, 1999, 6(1): 42-43 |
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| Authors: | Pan Qin Wang Jirong Li Juan et al. |
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| Affiliation: | Pan Qin,Wang Jirong,Li Juan,et al.Department of Oncology,The Second Affiliated Hospital of NanJing Medical University,Nanjing 210011 |
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| Abstract: | Objective To evaluate the effect of 10-HCPT instillation pleural or abdominal cavity in the management of malignant pleural effusion or ascites. Methods Twenty-seven cases with malignant pleural effusion or ascites were treated by instillating 10-HCPT into pleural or abdominal cavity. Results CR was achieved in 9 cases ,PR in 13 cases, NR in 5 cases. The overall response rate was 81.5%(22/27).This local regimen was well tolerated without any undesired side effects. Conclusion This approach of therapy was superior to other management modlities in terms of higher efficacy and lower toxicity. |
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| Keywords: | hydroxyl camptothecine Malignant pleural effusion or ascites Local regimen |
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