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| 一种简捷可靠的小鼠气管插管新方法 | |
| 引用本文： | 刘利辉,叶玲玉,谭渊明,刘昭前,William Hatton,DUAN Dayue. 一种简捷可靠的小鼠气管插管新方法[J]. 中国医师杂志, 2006, 8(8): 1019-1020 |
| 作者姓名： | 刘利辉 叶玲玉 谭渊明 刘昭前 William Hatton DUAN Dayue |
| 作者单位： | 1. 中南大学临床药理研究所,湖南,长沙,410078;Department of Pharmacology, University of Nevada School of Medicine, Reno, Nevada, 895557 USA 2. Department of Pharmacology, University of Nevada School of Medicine, Reno, Nevada, 895557 USA 3. 中南大学临床药理研究所,湖南,长沙,410078 |
| 基金项目： | N.I.H.P20RR15581，N.I.H.R01HL63914 |
| 摘 要： | 目的探索一种安全、高效的小鼠气管插管新方法。方法这种新方法是在小鼠颈前作一小切口,显露气管后,经口腔作气管内插管,费时仅约1 m in。结果经过1300多次实验,无一例失败,成功率达100%。结论这种简捷实用、安全可靠的小鼠气管插管新方法无需特殊设备及体位,一人操作即能完成,可显著提高以小鼠为实验动物模型的成功率。 |
| 关 键 词： | 插管法 气管内/方法 |
| 收稿时间： | 2006-05-10 |
| 修稿时间： | 2006-05-10 |
A novel method for easy and reliable endotracheal intubation in the mouse |
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| LIU Li-hui,YE Ling-yu,TAN Yuan-ming,LIU Zhao-qian,William Hatton,DUAN Dayue. A novel method for easy and reliable endotracheal intubation in the mouse[J]. Journal of Chinese Physician, 2006, 8(8): 1019-1020 | |
| Authors: | LIU Li-hui YE Ling-yu TAN Yuan-ming LIU Zhao-qian William Hatton DUAN Dayue |
| Abstract: | Objective To explore a safe and efficient method for endotracheal intubation in mice.Methods A small longitudinal incision was made in the middle of the neck in rats.After the trachea was exposed,the rats were undergone endotracheal intubation and the operation was completed in about 1 min.Results The success rate of intubation was 100% in over 1300 cases.Conclusion The whole procedure can be finished by one person without extra equipment and special mouse position.This novel and efficient method can significantly improve the success rate in using mice as animal models for in vivo studies. |
| Keywords: | Intubation intratracheal/ methods |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |