C-band pattern in lymphocytes of patients with soft tissue sarcomas |
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Authors: | Roland Berger Alain Bernheim Felix Mitelman Anders Rydholm |
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Affiliation: | 1. Department of Clinical Genetics, University of Lund, Sweden;2. Department of Orthopedic Surgery, University of Lund, Sweden;3. Laboratoire de Cytogénétique, Institut de Recherches sur les Maladies du Sang, Hôpital Saint-Louis, Paris France. |
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Abstract: | The pattern of heteromorphisms in the C-band-positive constitutive heterochromatin of human chromosomes No. 1, 9, and 16 was studied in peripheral lymphocytes of 45 patients with soft tissue sarcomas and 78 control individuals. The parameters of the heterochromatic regions analyzed were relative size, symmetry-asymmetry within homologous pairs, and incidence of inversions. No consistent differences were found in these parameters between controls and sarcoma patients. |
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Keywords: | Address requests for reprints to Prof. F Mitelman Department of Clinical Genetics University Hospital S-221 85 Lund Sweden. |
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