Cytogenetic analysis of SV40-transformed human breast epithelial cells |
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| Authors: | Catherine S. Rodgers Sally M. Hill Maj A. Hultén Sidney E. Chang Jacqueline Keen Joyce Taylor-Papadimitriou |
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| Affiliation: | 1. Regional Cytogenetics Laboratory, East Birmingham Hospital, Birmingham, England;2. Imperial Cancer Research Fund, Lincoln''s Inn Fields, London, England |
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| Abstract: | The SV40-transformed breast epithelial cell lines established by Chang et al. [1] were shown to be hypotetraploid and characterized by six chromosome markers: M1 i(1q), M2 del(1)(q21), M3 i(6p), M4 del(1)(q11), M5 t(8p;12q), and M6 dir dup(11)(p12→pter). The presence of common chromosome markers indicates that these cell lines are probably derived from the same original transformed cell. |
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| Keywords: | Address requests for reprints to Catherine S. Rodgers Regional Cytogenetics Laboratory East Birmingham Hospital Bordesley Green East Birmingham B9 5ST England. |
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