Detection of HIV-1 neutralizing antibodies by a simple, rapid, colorimetric assay |
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| Authors: | A J Langlois T J Matthews K J Weinhold S Chaffee M Hershfield D P Bolognesi |
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| Affiliation: | Duke University Medical Center, Department of Surgery, Durham, NC 27710. |
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| Abstract: | A rapid, simple, reproducible and semi-quantitative assay to measure neutralizing antibodies has been developed. It employs a unique cell line which is exquisitively sensitive to infection with all HIV isolates tested. The assay is amenable to microtiter formulation as well as analysis by automation. |
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