多普勒组织成像技术对高血压患者左室舒张功能的研究

目的:探讨多普勒组织成像(Doppler Tissue Imaging,DTI)技术评价高血压病(EH)患者左室舒张功能的价值,以寻求早期获得高血压左室舒张功能可靠而客观的方法。方法:36例正常人和27例EH患者(伴心肌肥厚者15例和不伴心肌肥厚者12例),用DTI法分别检测正常人及EH患者二尖瓣环室间隔侧及侧壁侧舒张早期运动速度(Ea)、舒张晚期运动速度(Aa)及Ea/Aa,并用二尖瓣血流多普勒法检测舒张期血流速度E、A及E/A以作比较。结果:正常人Ea、Aa、Ea/Aa与年龄相关,EH患者相关性降低;高血压组Ea、Ea,/Aa较正常人减低有显著性意义(P<0.01),且心室肥厚(LVH)组比非肥厚(non-LVH)组降低更明显。EH患者二尖瓣血流频谱E、E/A虽降低,但左室肥厚组与非肥厚组无明显差异(P>0.05)。结论:DTI法能简便准确地定量EH患者二尖瓣环舒张期运动速度的改变,从而准确判断舒张功能受损程度,此法优于二尖瓣血流频谱法。

Study of Diastolic Function in Hypertensive Patients by Doppler Tissue Imaging

Objective To explore the value of Doppler tissue imaging (DTI) in assessing the left ventricular diastolic func- tion of patients with essential hypertension(EH).Methods 36 cases normotensive and 27 cases hypertensive Patients[ 15 Pa- tients with left ventinculer hypertrophy (LVH) and 12 Patients without left ventinculer hypertrophy (non-LVH)] Mitral annular velocity in early diastole(Ea) and late diastole(Aa) and Ea/Aa in normal and hypertensive Patient by DTI were studied and also mitral inflow velocity E...