补肾活血方治疗老年性骨质疏松性椎体压缩性骨折临床观察

目的 研究补肾活血方联合经皮椎体后凸成形术(percutaneous kyphoplasty,PKP)治疗老年性骨质疏松性椎体压缩性骨折(osteoporotic vertebral compression fracture,OVCF)的疗效,探究中医药治疗老年性OVCF更为有效的治疗方案.方法 按随机对照设计,选取2...

Clinical study on Bushen Huoxue Recipe in the treatment of senile osteoporotic vertebral compression fracture

Objective To study the efficacy of Bushen Huoxue Recipe combined with percutaneous kyphoplasty(PKP) in the treatment of senile osteoporotic vertebral compression fracture(OVCF), and to explore the effective treatment of senile OVCF.Methods A total of 60 patients with senile OVCF in The First Affiliated Hospital of Hunan University of Chinese Medicine from January 2019 to December 2019 were divided into treatment group(n=30) and control group(n=30) according to random table method.The patients in the two groups were treated with PKP and performed routine anti-osteoporosis therapy after operation. The patients in the treatment group were treated with Bushen Huoxue Recipe on the basis of the control group for 3 months. The pain visual analogue scale(VAS) and Oswestry disability index(ODI) were evaluated before operation, 1 week, 1 month and 3 months after operation. Chinese osteoporosis-targeted quality of life(COQOL) score and T value of osteoporosis were compared between the two groups before and 3 months after operation. The clinical efficacy of the two groups was evaluated before and 3 months after operation. Results Three months after operation, the total effective rate of the treatment group was 90.00%, higher than that of the control group 83.33%(P<0.05). The VAS score, ODI index of 1 week, 1 month and 3 months of the two groups were lower than those before operation;one week after operation, there was no significant difference in VAS score between the observation group and the control group(P>0.05);VAS score of observation group was lower than control group at 1 and 3 months after operation(P<0.05);the ODI score of the observation group was lower than that of the control group at the same time after operation(P<0.05). Three months after operation, there was no significant difference in the T value of osteoporosis in the control group compared with that before operation(P>0.05), while the T value of osteoporosis in the observation group was lower than that before operation(P<0.05), and the T value of osteoporosis in the observation group was lower than that in the control group(P<0.05). Three months after operation,COQOL score of 4 dimensions in two groups decreased compared with that before operation(P <0.05), and COQOL score of4 dimensions in observation group was lower than that in control group(P<0.05). Conclusion Bushen Huoxue Recipe combined with PKP is effective, safe and effective in the treatment of senile OVCF.