桃红四物汤联合五苓散对跟骨骨折术后患者骨折愈合及关节肿胀的影响

[目的]探讨桃红四物汤联合五苓散对跟骨骨折术后患者骨折愈合及关节肿胀的影响.[方法]将83例跟骨骨折患者随机分为中药组42例和对照组41例.2组患者均给予行切开复位内固定术治疗,对照组患者术后给予口服碳酸钙D3片和常规功能锻炼治疗,中药组患者在对照组基础上给予加服桃红四物汤联合五苓散治疗,疗程为1个月.观察2组患者术前...

Effect of Taohong Siwu Decoction Plus Wuling Powder on Fracture Healing and Joint Swelling in Calcaneal Fracture Patients after Operation

Objective To investigate the effect of Taohong Siwu Decoction plus Wuling Powder on fracture healing and joint swelling in calcaneal fracture patients after operation. Methods A total of 83 patients with calcaneal fracture were randomly divided into Chinese medicine(CM)group(n = 42)and control group(n = 41). Patients in both groups were treated with open reduction and internal fixation(ORIF). Additionally,the control group was given calcium carbonate D3 tablets orally and routine functional exercise after surgery, and the CM group was treated with Taohong Siwu Decoction plus Wuling Powder orally on the basis of the treatment for the control group.The treatment lasted for one consecutive month. The outcomes included the preoperative and postoperative American Orthopedic Foot Ankle Society(AOFAS)scores and the levels of fracture healing indexes of serum alkaline phosphatase(ALP),insulin-like growth factor(IGF),procollagen type Ⅰ carboxyl-terminal peptide(PICP),and bone morphogenetic protein(BMP),and postoperative limb swelling degree,visual analogue scale(VAS)pain scores, fracture healing time, discharge time and postoperative complications in the two groups.Results(1)During the trial,one case from each group was lost to follow-up,and a total of 81 patients completed the follow up,41 cases from the CM group and 40 cases from the control group.(2)On the 7 th day after surgery,the swelling-disappearance rate of the affected limb in the CM group(swelling degree being zero)was 78.0%(32/41), which was significantly higher than that in the control group 50.0%(20/40), and the difference was statistically significant(P<0.05).(3)On the 7 th day after surgery, pain VAS scores of both groups were significantly lower than the scores on the 3 rd day after surgery(P<0.05),and VAS scores of the CM group were significantly lower than those of the control group, the difference being statistically significant(P<0.01).(4)Three and 6 months after surgery,AOFAS scores in both groups were significantly higher than those before surgery(P<0.05). The AOFAS scores in both groups 6 months after surgery were significantly higher than the scores 3 months after surgery(P<0.05). The intergroup comparison showed that the AOFAS scores of the CM group were significantly higher than those of the control group 3 months after surgery, and the difference was statistically significant(P<0.01).(5)One month after surgery,the serum levels of ALP,IGF,PICP and BMP in the two groups were significantly increased compared with those before syrgery(P<0.05),and the serum levels of ALP,IGF and PICP in the CM group were significantly higher than those in the control group,the differences being statistically significant(P<0.05).(6)Compared with the control group,the fracture healing time and discharge time of the CM group were significantly shortened, and the incidence of postoperative complications was significantly reduced, the differences being statistically significant(P<0.01). Conclusion Taohong Siwu Decoction plus Wuling Powder can significantly promote fracture healing in patients with calcaneal fracture after internal fixation, improve postoperative foot and ankle function, relieve postoperative pain and joint swelling,reduce the incidence of postoperative complications,and shorten fracture healing time and discharge time.