基于“舌脉症3步法”探究附子理中丸加味治疗脾阳虚型慢性浅表性胃炎

目的:观察附子理中丸加味治疗脾阳虚型慢性浅表性胃炎的临床疗效。方法:采用"舌脉症3步法"对慢性浅表性胃炎患者进行辨证分型,将80例脾阳虚型慢性浅表性胃炎患者按照随机数字表法分为观察组和对照组,每组各40例。对照组给予奥美拉唑肠溶胶囊治疗,观察组给予附子理中丸加味治疗。比较两组患者的临床疗效、胃镜疗效、幽门螺杆菌(helicobacter pylori,Hp)清除率及治疗前后中医证候积分变化情况。结果:对照组有效率为72.5%,观察组有效率为95.0%,两组患者临床疗效比较,差异具有统计学意义(P<0.05)。两组患者治疗后中医证候积分低于本组治疗前,且治疗后观察组低于对照组,差异具有统计学意义(P<0.05)。对照组Hp清除率为55.56%,观察组Hp清除率为81.58%,两组患者Hp清除率比较,差异具有统计学意义(P<0.05)。对照组有效率为70.0%,观察组有效率为92.5%,两组患者胃镜疗效比较,差异具有统计学意义(P<0.05)。两组患者复发率比较,差异具有统计学意义(P<0.05)。结论:附子理中丸加味治疗脾阳虚型慢性浅表性胃炎,可改善患者的临床症状,增强胃黏膜损伤的修复力和Hp清除力,进而验证采用"舌脉症3步法"对慢性浅表性胃炎患者进行辨证分型的可行性。

Clinical Study on Supplemented Aconite Center-Regulating Pill in the Treatment of Chronic Superficial Gastritis with Spleen Yang Deficiency Syndrome Based on"Three-Step for Treating Tongue Pulse Syndrome"

Objective:To observe the clinical curative effect of Supplemented Aconite Center-Regulating Pill on chronic superficial gastritis with spleen yang deficiency syndrome.Methods:A total of 80 patients with chronic superficial gastritis with spleen yang deficiency syndrome were randomly divided into observation group and control group according to"three-step for treating tongue pulse syndrome",with 40 cases in each group.The control group was treated with Omeprazole Enteric Coated Capsule,while the observation group was treated with Supplemented Aconite Center-Regulating Pill.The clinical efficacy,gastroscopic efficacy,helicobacter pylori(Hp)clearance rate and the changes of TCM syndrome score before and after treatment were compared between the two groups.Results:The effective rate was 72.5%in the control group and 95.0%in the observation group.There was significant difference between the two groups(P<0.05).The TCM syndrome score of the two groups after treatment was lower than that before treatment,and the index of the observation group after treatment was lower than that of the control group,and the difference was statistically significant(P<0.05).The Hp clearance rate was 55.56%in the control group and 81.58%in the observation group.There was significant difference between the two groups(P<0.05).The effective rate was 70.0%in the control group and 92.5%in the observation group.There was significant difference between the two groups(P<0.05).There was also significant difference in the recurrence rate between the two groups(P<0.05).Conclusion:Supplemented Aconite Center-Regulating Pill in the treatment of chronic superficial gastritis with spleen yang deficiency syndrome can improve the clinical symptoms of patients,enhance the repair and Hp clearance of gastric mucosal injury,and then verify the feasibility of syndrome differentiation of patients with chronic superficial gastritis by"three-step for treating tongue pulse syndrome".