Gender based differences in management and outcomes of cholecystitis |
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Authors: | Anahita Dua Arshish Dua Sapan S. Desai SreyReath Kuy Rishika Sharma Sarah E. Jechow Jason McMaster Bhavin Patel SreyRam Kuy |
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Affiliation: | 1. Department of Surgery, Medical College of Wisconsin, 9200 W Wisconsin Avenue, Milwaukee, WI 53226, USA;2. Center for Translational Injury Research, Department of Surgery, University of Texas–Houston, Houston, TX, USA;3. University General Hospital, Houston, TX, USA;4. University of Texas Medical School at Houston, Houston, TX, USA;5. Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA;6. Department of Cardiothoracic and Vascular Surgery, University of Texas Medical School at Houston, Houston, TX, USA;g Department of Surgery, Duke University, Durham, NC, USA |
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Abstract: | BackgroundDuring the reproductive years, women have a 4-fold higher prevalence of gallstones than men, making gallbladder disease a critically important topic in women's health. Among age-matched women and men hospitalized for cholecystitis, gender based differences in demographics, management, and economic and clinical outcomes were identified.MethodsA cross-sectional study was conducted using the Nationwide Inpatient Sample. Outcomes were mortality, complications, length of stay, and cost.ResultsWomen accounted for 65% of admissions for cholecystitis, with women more likely to have shorter time to surgery (1.6 vs 1.9 days) and laparoscopy (86 vs 76%) (P < .05). After cholecystectomy, women had lower mortality (.6% vs 1.1%), fewer complications (16.9 vs 24.1), shorter lengths of stay (4.2 vs 5.4 days), and lower costs ($10,556 vs $13,201) (P < .05). On multivariate analysis of age-matched patients, women had lower odds of mortality (odds ratio [OR], .75), complications (OR, .86), length of stay (OR, .95), and cost (OR, .93). Longer time to surgery and open cholecystectomy were independent predictors of worse outcomes.ConclusionsIn cholecystitis and cholecystectomy, women have better clinical and economic outcomes then age-matched men. |
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Keywords: | Outcomes Gender Cholecystectomy Biliary disease |
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