山东省恙虫病血清流行病学调查研究

目的：对山东省不同地区人间和鼠间恙虫病感染情况进行较为全面的了解。方法：采用IFAT、M—CFT等血清学方法在全省10个市开展不同人群间和鼠间调查。结果：首次在我省黄河以北地区检出恙虫病感染鼠；在我省褐家鼠中检出恙虫病立克次体抗体，血清学显示其感染率达10％；通过血清学检查还从大仓鼠中检出恙虫病立克次体抗体，其感染率达15．63％。通过血清学方法证实我省潍坊、菏泽存在恙虫病人间感染。结论：我省广泛存在恙虫病疫区，黑线姬鼠为主要传染源，其血清学阳性率达19．46％，但褐家鼠甚至包括大仓鼠也有可能是本病的重要传染源；山东省恙虫病的流行极有可能存在多样性。

Seroepidemiological Investigation on Scrub Typhus in Shandong Province

Objective To learn the epidemic status of scrub typhus in Shandong province.Methods IFAT and M-CFT were used and about 10 cities joined the programme.Different population and rats were sampled for detection.Results Some rats infected with scrub typhus were firstly found at the north regions of Yellow River in Shandong province.The infection rates among R.norvegicus and C.triton were 10.00% and 15.63% respectively.The infection of scrub typhus among human was firstly confirmed in Weifang city and Heze city.Conclusion The study showed that there are extensive epidemic regions with scrub typhus in Shandong province.A.agrarius was the major host,whose serological positive rate was up to 19.46%.R.norvegicus as well as C.triton may also be the important reservoirs.The epidemiological diversity may exists in the province.