沙漠负重行军者热休克蛋白与一氧化氮的关系

目的　探讨沙漠干热环境负重应激行军者热休克蛋白 (HSPs)与机体一氧化氮 (NO)及其一氧化氮合成酶 (NOS)的关系。方法　对在沙漠干热环境中 15kg负重、分别以 3 5km/h和 5 0km/h速度行军 1,2 ,3h的 57名战士和 14名对照血浆HSP70和HSP2 7、NOS和NOS等进行研究。结果　在 15kg负重条件下 ,不管是 3 5km /h还是5 0km /h ,各行军组HSP70与对照组及各行军时间组间HSP70均无显著性差异 (P >0 0 5) ;各行军时间组HSP2 7明显高于对照组 (P <0 0 5) ,各行军时间组间HSP2 7无显著性差异 (P >0 0 5) ;各行军时间组NO明显低于对照组(P <0 0 5)。 3 5km /h行军 3h组NO明显低于行军 1,2h组 (P <0 0 5) ;3 5km/h行军 1h组NOS明显高于对照和行军 3h组 (P <0 0 5) ;5 0km/h行军 2h组NOS明显低于对照和其它行军时间组 (P <0 0 5)。结论　沙漠干热环境应激负重行军者血浆HSP2 7与NO及其NOS密切相关 ,HSP70与NO及其NOS关系不大

Relation between heat shock proteins and nitric oxide in marchers with load in desert

ObjectiveTo explore the relation between heat shock prot eins(HSP70 and HSP27) and nitric oxide(NO) and nitric oxide synthase(NOS) in mar chers in dry-heat desert.MethodsThe plasma HPS70,HSP27,NO and NOS of 57 marchers at different speed of different time with 15?kg and of 14 controls were detecte d.ResultsWith 15?kg at both 3.5 and 5.0?km/h,the p lasma HSP27 in the marching groups were much more than the control( P <0 05) ;the plasma HPS70 in the marching groups were slightly more than the control( P >0 05);and the plasma NO in the marching groups were much lower than the con trol.NO for 1 hour was much more than the other marching groups at 3.5?km/h.As for NOS,NOS for 1 hour was much more than the control and the other groups at 3. 5?km/h;and NOS for 2 hour was much lower than the control and the other groups at 5.0?km/h.ConclusionIn the case of loading,there was a close rela tion between HSP27 and NO,NOS and no relation between HSP70 and NO and NOS in ma rchers in dry-heat desert.