| 绿海葵中的核苷类成分 |
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| 引用本文： | 禚如朋,付宏征,张礼和,林文翰.绿海葵中的核苷类成分[J].中草药,2001,32(4):289-291. |
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| 作者姓名： | 禚如朋 付宏征 张礼和 林文翰 |
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| 作者单位： | 北京大学天然药物及仿生药物国家重点实验室，北京 100083 |
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| 摘 要： | 目的：为了寻找抗肿瘤的活性成分，方法：利用溶剂法和色谱法对绿海葵进行了研究。结果：分离得到5个核苷，经波谱学解析鉴定为2－羟基嘌呤核苷（1），脱氧肌苷（II），1－甲基黄嘌呤核苷（III），脱氧鸟苷（IV），脱氧核糖胸腺嘧啶（V），结论：III为一新天然产物，其余均为海洋生物中首次发现。
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| 关 键 词： | 绿海葵 核苷 1－甲基黄嘌呤核苷 成分 |
| 文章编号： | 0253-2670(2001)04-0289-03 |
| 收稿时间： | 2000/11/16 0:00:00 |
| 修稿时间： | 2000年11月16 |
Nucleosides from Anthopleura stell |
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| ZHUO Rupeng,FU Hongzheng,ZHANG Lihe and LIN Wenhan.Nucleosides from Anthopleura stell[J].Chinese Traditional and Herbal Drugs,2001,32(4):289-291. |
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| Authors: | ZHUO Rupeng FU Hongzheng ZHANG Lihe and LIN Wenhan |
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| Institution: | State Key Laboratory of Natural and Biomimetic Drugs, Beijing University of Medical Sciences, Beijing 100083, China;State Key Laboratory of Natural and Biomimetic Drugs, Beijing University of Medical Sciences, Beijing 100083, China;State Key Laboratory of Natural and Biomimetic Drugs, Beijing University of Medical Sciences, Beijing 100083, China;State Key Laboratory of Natural and Biomimetic Drugs, Beijing University of Medical Sciences, Beijing 100083, China |
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| Abstract: | To study the chemical constituents of sea anemone, Anthopleura stell Verrill.Methods The chemical constituents were isolated and purified by chromatographic methods and their structures elucidated by chemical evidences and spectra data.Results 5 nucleosides were obtained and identified from the ethanolic extract as 2-hydroxy purine (Ⅰ); deoxyinosine (Ⅱ); 1-methylxanthosine (Ⅲ); deoxyguanosine (Ⅳ), and deoxyribo-thymidine (Ⅴ).Conclusion Compound Ⅲ was a new natural product， while the others were found from sea anemone for the first time. |
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| Keywords: | Anthopleura stell (Verrill) nucleoside 1 methylxanthosine |
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