糖尿病合并无症状性尿路感染的特点及预防措施

目的探讨糖尿病合并无症状性尿路感染的临床特点及预防措施. 方法对1999～2004年10月我院所收治 100例无症状性尿路感染患者,其中75例糖尿病、25例非糖尿病患者进行临床分析. 结果糖尿病合并无症状性尿路感染患者明显高于非糖尿病合并无症状性尿路感染患者,前者是后者3倍;年龄越大,发生率越高,尤其糖尿病组更明显,两组对比差异有非常显著性(P<0.001);糖尿病组女性发生率高于男性,分别为80%、20%;老年糖尿病的女性患者发生率最高,占糖尿病组的53%;细菌学检查结果:两组的病原菌分布仍以革兰阴性杆菌为主,分别为72%和64%;糖尿病组的真菌感染发病率(11%)高于非糖尿病组(4%). 结论糖尿病合并无症状性尿路感染发生率高,特别是成年女性,发生率随年龄增加而增加;在积极控制血糖基础上,寻找有效措施预防无症状性尿路感染的发生是减少糖尿病肾损害的有效方法.

Urinary Tract Infections in Diabetes Mellitus Patients: Clinical Characteristics and Prevention

OBJECTIVE To investigate the c li nical characteristics and prevention of asymptomatic urinary tract infections in diabetes mellitus patients. METHODS An analysis of clinical features of 100 hospitalized cases from 1999 to Oct 2004 was performed on asymptomatic ur inary tract infections between 75 cases with diabetes and 25 cases without it. RESULTS The asymptomatic urinary tract in fections rate in diabetes group was sharply higher than that of the non-diabete s one(about 3 times) and the rate was growing along with the development of age,especially with diabetes mellitus,there was a remarkable difference between the two groups(P<0.001).the rate of the female patients was h igher than that of the male ones(the rates were 80% and 20%,respectively).A mong old patients with diabetes mellitus,the rate in female patients was the hi ghest up to 53%.The results of bacterial examination in both groups indicated t hat the main pathogens were Gram negative organisms(the rates were 72% and 64%,respectively).The fungal infection rate in diabetes group(11%) was higher t han non-diabetes one(4%). CONCLUSIONS The asymptomatic urinary tra ct infections rate in diabetes is high,especially among adult females,the rate growing along with the development of age.The key to reduce the damage to the k idney with diabetes is to look for effective measures and prevent occurrence of the asymptomatic urinary tract infections at the basis of controlling blood gluc ose.