肺原发性浆细胞瘤1例报告并文献复习

目的 提高对原发性肺浆细胞瘤的认识。方法 对1例临床确诊为原发性肺浆细胞瘤患者的临床资料进行分析,通过Pubmed检索2000-2014年所发表相关文献,结合文献复习。结果 原发性肺浆细胞瘤是一种极为罕见的肺部肿瘤,属于髓外浆细胞瘤的范畴。患者多缺乏临床症状,影像学上表现为肺内单发或多发结节影,缺乏特异性,容易误诊。其诊断主要依赖肺部肿块的病理活检,并应排除骨髓原发病灶。对于局限性的病灶可采取手术治疗或放疗,多发病灶可采取化疗。结论 对于此类表现为肺部结节、肿块影的病例应当尽早进行穿刺活检以获取病理诊断,以免误诊误治。

Primary pulmonary plasmacytoma: a case report and review of the literature

Objective To describe the characteristics of primary pulmonary plasmacytoma. Methods One patient with primary pulmonary plasmacytoma was described and relevant literatures were reviewed. Results Primary pulmonary plasmacotyma is a very rare form of extramedullary plasmacytoma.Patients with this disease usually have little symptoms. Primary pulmonary plasmacytoma often presents as solitary or multiple nodular mass lesions, but these lesions lack specific radiographic features and are easily lead to misdiagnosis. The diagnosis of primary pulmonary plasmacotyma is based on the histological confirmation of plasma cell infiltration in lung lesions. Additionally, it requires normal bone marrow, normal skeletal survey, no related organ or tissue impairment, and no M protein in serum and/or urine. Most cases of solitary pulmonary plasmacytoma can be treated with surgical resection and/or irradiation, and combination chemotherapy is effective for cases of diffuse pulmonary infiltration. Conculsion Biopsy and pathologic diagnosis is very important to patients who present as solitary or multiple nodular mass lesions to avoid misdiagnosis and mistreatment.