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中药妇痛宁煎剂对子宫内膜异位症模型鼠免疫功能的影响
引用本文:李淑萍,白淑芳,吴晓凤,张利平. 中药妇痛宁煎剂对子宫内膜异位症模型鼠免疫功能的影响[J]. 武警医学, 2001, 12(5): 271-273
作者姓名:李淑萍  白淑芳  吴晓凤  张利平
作者单位:武警医学院附属医院中医科,天津,300162
摘    要: 目的探讨中药复方妇痛宁煎剂治疗子宫内膜异位症的免疫学机理.方法建造SD大鼠EMT模型.40只大鼠随机分为空白对照组、模型对照、口服中药、口服盐水4组.并监测各组大鼠血清免疫球蛋白(IgA、IgG、IgM);脾脏T淋巴细胞亚群(CD3、CD4、CD8、CD4/CD8)水平;NK细胞、IL-1、IL-6活性.结果妇痛宁能抑制增强的体液免疫反应,改善细胞免疫功能,提高NK细胞活性,降低血清IL-1、IL-6的分泌水平.结论中药复方妇痛宁煎剂能较好调节子宫内膜异位症紊乱的免疫机能.

关 键 词:子宫内膜异位症  中药  免疫功能  大鼠  
收稿时间:2000-05-09
修稿时间:2000-05-09

Effect of Futongning decoction on immune function of rats with endomefriosis
Li Shuping,Bai Shufang,Wu Xiaofeng and Zhang Liping. Effect of Futongning decoction on immune function of rats with endomefriosis[J]. Medical Journal of the Chinese People's Armed Police Forces, 2001, 12(5): 271-273
Authors:Li Shuping  Bai Shufang  Wu Xiaofeng  Zhang Liping
Affiliation:Li Shuping,Bai Shufang,Wu Xiaofeng and Zhang Liping.Department of Chinese Medicine,Affiliated Hospital,Medical college of Chinese People's Armed Police Force,Tianjin 300162,China
Abstract:Objective To investigate the therapeutic effect of traditional Chinese medicine Futongning decoction (FTN) on endometriosis (EMT) and ots immunological mechanism.Methods EMT model of SD rats were set up .50 rats were divided into four groups:normal group.EMT model group,FTN group and physiological saline group.The levels of serum IgA,IgG,IgM,and the function of CD 3,CD 4,CD 8,CD 4/CD 8,and the activity of natural killer (NK) cells,and the secreting levels of IL-1,IL-6 in serum were measured.Results FTN suppressed the increased humoral immunereactio in EMT improved the function of cell immunity,enhanced significantly NK activity,and reduced the secreting levels of IL-1,IL-6 in serum.Conclusions FTN can relieve the disturbancesof immune function in EMT.
Keywords:Endometriosis Traditional Chinese medicine Immune function Rats
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