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环孢素A联合CAG方案治疗中高危低增生性骨髓增生异常综合征疗效分析
引用本文:马清君,冷青,季征,张桂敏,吴音. 环孢素A联合CAG方案治疗中高危低增生性骨髓增生异常综合征疗效分析[J]. 中国全科医学, 2010, 13(5): 529-530
作者姓名:马清君  冷青  季征  张桂敏  吴音
作者单位:辽宁省鞍山市中心医院血液科,114001
摘    要:目的分析环孢素A(CsA)联合CAG方案〔粒细胞集落刺激因子(G-CSF)+阿糖胞苷(Ara-C)阿柔比星(ACLA)〕治疗中高危低增生性骨髓增生异常综合征(hypo-MDS)的临床疗效。方法应用CsA联合CAG方案治疗17例中高危hypo-MDS患者,随诊观察有效率及副作用发生情况。结果治疗后有效率为82.4%(14/17),全部患者未发现严重毒副作用。结论CsA联合CAG方案治疗中高危hypo-MDS患者安全、有效,但其长期疗效需进一步观察。

关 键 词:环孢素A  CAG方案  骨髓增生异常综合征

Clinical Effect of Cyclosporin A Combined with CAG Regiment on Moderate-or High-risk Hypoplastic Myelodysplastic Syndrome
MA+Qing-jun,LENG+Qing,JI+Zheng,et+al. Clinical Effect of Cyclosporin A Combined with CAG Regiment on Moderate-or High-risk Hypoplastic Myelodysplastic Syndrome[J]. Chinese General Practice, 2010, 13(5): 529-530
Authors:MA+Qing-jun  LENG+Qing  JI+Zheng  et+al
Affiliation:MA+Qing-jun,LENG+Qing,JI+Zheng,et+al.Department+of+Hematology,Liaoning+Anshan+Central+Hospital,Anshan+114001,China
Abstract:Objective To observe the clinical effect of cyclosporin A(CsA) with CAG regiment on moderate-or high-risk hypoplastic myelodysplastic syndrome(hypo-MDS).Methods Senventeen moderate-or high-risk hypo-MDS patients receiving CsA with CAG regiment treatment were followed up to observe the effectiveness and incidence of adverse reactions.Results The total effective rate of 17 patients was 82.4%(14/17).No serious side effects were noted.Conclusion The combined CsA and CAG regiment treatment is safe,effective in t...
Keywords:Cyclosporin A  CAG regiment  Myelodysplastic syndrome
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