| 芒果甙对实验性肝损伤大鼠酶及形态变化影响的研究 |
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| 引用本文： | 成海龙,李玉华,卞庆亚.芒果甙对实验性肝损伤大鼠酶及形态变化影响的研究[J].中国比较医学杂志,1999,9(1):24-27. |
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| 作者姓名： | 成海龙 李玉华 卞庆亚 |
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| 作者单位： | 1. 盐城卫生学校正常人体学学科组,盐城
2. 中国医学科学院药用植物研究所 |
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| 摘 要： | 利用三种实验模型研究了芒果甙的肝保护作用。三种大鼠肝损伤模型分别由醋氨酚(A-PAP)，四氯化碳(CCI4)和D-氨基半乳糖(D-GaIN)诱导形成。芒果甙能明显降低三种肝损伤模型大鼠血清的谷丙转氨酶(GPT)和谷草转氨酶(GOT)水平，病理检查结果显示．芒果甙并能使大鼠肝损伤显著减轻，表明其具有一定的肝保护作用。
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| 关 键 词： | 芒果甙 实验性肝损伤 模型大鼠 肝保护作用 鼠肝 D-氨基半乳糖 谷草转氨酶 GPT 诱导形成 利用 |
Effects of Enzyme and Morphological Change of Mangiferin on Exp erimental Liver Damage in Rats |
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| Cheng Hailong,et al.Effects of Enzyme and Morphological Change of Mangiferin on Exp erimental Liver Damage in Rats[J].Chinese Journal of Comparative Medicine,1999,9(1):24-27. |
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| Authors: | Cheng Hailong |
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| Abstract: | The mangiferin was investigated on the hepatoprotective effects in three kinds of
models of experimentally-induced liver injuries in rats. The models were induced by
acetaminophen, carbon tetrachloride, and D-GalN. The results showed that mangiferin caused
significant reduction of the elevated enzyme levels of serum glutamate oxaloacetate
transminase, serum glutamate pyruvate transminase in model rats, and alleviated the
pathological damages in livers of the model rats. These findings are suggestive of the potent
hepatoprotective effects of mangiferin. |
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| Keywords: | Mangiferin GLUtamate oxaloacetate transminase (GOT) GLUtamate pyruvate transminase (GPT) Hepatoprotective effect |
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