欧瑞血活素治疗慢性重症病毒性肝炎疗效观察

目的　探讨血活素治疗慢性重症病毒性肝炎 (CSH)的疗法。方法　治疗组 5 0例 ,在常规治疗基础上加用血活素 15ml于 10 %葡萄糖注射液 2 5 0ml中静滴 ,qd× 4wk。对照组 5 0例 ,仅用护肝、退黄、支持、抗感染及利尿等常规治疗。结果　治疗组SB和ALT较治疗前明显下降 (P <0 .0 1) ,显效率为 5 2 % ,总有效率为 86 % ,均优于对照组。结论　血活素是安全有效的慢性重症肝炎辅助治疗药物。

Therapeutic effect of blood activing polypeptide on the treatment of chronic severe viral hepatitis

OBJECTIVE: To study the therapeutic effect of blood activating polypeptide on chronic severe viral hepatitis (CSH) and the method used. METHODS: The treated group included 50 CSH patients (male 82, female 8, age 39 +/- 9). Based on routine treatments, they were intravenously injected with 15 ml blood activating polypeptide dissolved in 250 ml of 10% glucose, qd x 4 wks. The control group contained 50 CSH patients (male 3, female 7, age 38+/-12). They were only treated with routine treatments for liver protection, jaundice regression, health maintenance, anti-infection and diuresis. RESULTS: The SB and ALT in treated patients decreased obviously (P < 0.01) after treatment, the prominent efficacy was 52%, the total efficacy was 86%, all were superior to the control group. CONCLUSIONS: Blood activating polypeptide is safe, reliable and effective in the treatment of CSH.